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. 2025 Oct 9;15:35271. doi: 10.1038/s41598-025-17063-5

Table 3.

Multivariable-adjusted odds ratios (95% CIs) for endometrial cancer across tertiles of energy-adjusted total, high-fat, low-fat dairy and butter intake.

T1 T2 T3 P-value for trend
Total dairy
Crude 1.00(ref) 0.17 (0.10–0.31) 0.43 (0.26–0.72) < 0.01
Model 1 1.00 (ref) 0.19 (0.11–0.35) 0.50 (0.30–0.84) < 0.01
Model 2 1.00 (ref) 0.14 (0.06–0.30) 0.31 (0.16–0.61) < 0.01
High-fat dairy
Crude 1.00 (ref) 0.24 (0.14–0.42) 0.55 (0.33–0.91) 0.01
Model 1 1.00 (ref) 0.25 (0.14–0.44) 0.63 (0.38–1.06) 0.05
Model 2 1.00 (ref) 0.18 (0.09–0.37) 0.39 (0.20–0.76) 0.01
Low-fat dairy
Crude 1.00 (ref) 0.39 (0.23–0.66) 0.46 (0.27–0.77) 0.01
Model 1 1.00 (ref) 0.38 (0.22–0.66) 0.39 (0.23–0.67) < 0.01
Model 2 1.00 (ref) 0.31 (0.15–0.63) 0.37 (0.19–0.72) < 0.01
Butter
Crude 1.00 (ref) 1.02 (0.61–1.77) 1.07 (0.64–1.48) 0.78
Model 1 1.00 (ref) 1.02 (0.60–1.75) 1.08 (0.64–1.83) 0.76
Model 2 1.00 (ref) 1.20 (0.63–2.28) 0.84 (0.43–1.63) 0.63

Data are presented as OR and 95% CI. Significant OR and 95% CI and corresponding p-values are highlighted in bold.

The analysis of Conditional logistic regression was used to determine the OR and 95% confidence interval.

Model 1: adjusted for age and waist circumference.

Model 2: additionally adjusted for physical activity, menarche age, first pregnancy age, breastfeeding history, family history of endometrial cancer, family history of cancer, menopausal status, oral contraceptive pills use, hormone replacement therapy use, polycystic ovary syndrome history, energy intake, and dietary fiber intake.