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Annals of Surgery logoLink to Annals of Surgery
. 1986 May;203(5):558–567. doi: 10.1097/00000658-198605000-00017

Selective drainage for pancreatic, biliary, and duodenal obstruction secondary to chronic fibrosing pancreatitis.

H J Sugerman, G R Barnhart, H H Newsome
PMCID: PMC1251171  PMID: 3707234

Abstract

Twenty-eight patients underwent surgery for intractable pain, duodenal or extrahepatic biliary obstruction secondary to chronic pancreatitis. Eleven had pancreatic duct obstruction alone, six biliary obstruction alone, seven combined pancreatic and biliary, two combined biliary and duodenal, one combined pancreatic and duodenal, and one simultaneous pancreatic, biliary, and duodenal obstruction. Pancreatitis was secondary to alcohol in all but one case. The following operations were performed: longitudinal pancreatojejunostomy (20), choledochoduodenostomy (8), choledochojejunostomy (7), cholecystojejunostomy (1), and gastrojejunostomy (4). Of the 20 patients with pancreatic duct drainage, pain relief was complete in 11 and partial in six. Initial incomplete relief of pain, or recurrence, stimulated further diagnostic procedures, leading to improvement or correction of the problem in five patients. A significant (p less than 0.01) fall in alkaline phosphatase (935 +/- 228 to 219 +/- 61 U/L) occurred following surgery. One patient was subsequently found to have pancreatic carcinoma. Two patients were lost to follow-up and four patients died (one perioperative and three late). In conclusion, the possibility of pancreatic, biliary, and duodenal obstruction must be considered in symptomatic patients with chronic pancreatitis. Surgery must be individualized. Drainage procedures, either alone or in combination, are associated with a low morbidity and improved clinical condition and may be preferable to resection in the surgical management of these patients.

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Selected References

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  1. Afroudakis A., Kaplowitz N. Liver histopathology in chronic common bile duct stenosis due to chronic alcoholic pancreatitis. Hepatology. 1981 Jan-Feb;1(1):65–72. doi: 10.1002/hep.1840010111. [DOI] [PubMed] [Google Scholar]
  2. Ammann R. W., Akovbiantz A., Largiader F., Schueler G. Course and outcome of chronic pancreatitis. Longitudinal study of a mixed medical-surgical series of 245 patients. Gastroenterology. 1984 May;86(5 Pt 1):820–828. [PubMed] [Google Scholar]
  3. Aranha G. V., Prinz R. A., Freeark R. J., Greenlee H. B. The spectrum of biliary tract obstruction from chronic pancreatitis. Arch Surg. 1984 May;119(5):595–600. doi: 10.1001/archsurg.1984.01390170091018. [DOI] [PubMed] [Google Scholar]
  4. Aranha G. V., Prinz R. A., Greenlee H. B., Freeark R. J. Gastric outlet and duodenal obstruction from inflammatory pancreatic disease. Arch Surg. 1984 Jul;119(7):833–835. doi: 10.1001/archsurg.1984.01390190071016. [DOI] [PubMed] [Google Scholar]
  5. Bradley E. L., 3rd, Clements J. L., Jr Idiopathic duodenal obstruction: an unappreciated complication of pancreatitis. Ann Surg. 1981 May;193(5):638–648. doi: 10.1097/00000658-198105000-00015. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Bradley E. L., 3rd Pancreatic duct pressure in chronic pancreatitis. Am J Surg. 1982 Sep;144(3):313–316. doi: 10.1016/0002-9610(82)90008-3. [DOI] [PubMed] [Google Scholar]
  7. Bradley E. L., 3rd, Salam A. A. Hyperbilirubinemia in inflammatory pancreatic disease: natural history and management. Ann Surg. 1978 Nov;188(5):626–629. doi: 10.1097/00000658-197811000-00007. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Brinton M. H., Pellegrini C. A., Stein S. F., Way L. W. Surgical treatment of chronic pancreatitis. Am J Surg. 1984 Dec;148(6):754–759. doi: 10.1016/0002-9610(84)90431-8. [DOI] [PubMed] [Google Scholar]
  9. Eckhauser F. E., Knol J. A., Strodel W. E., Achem S., Nostrant T. Common bile duct strictures associated with chronic pancreatitis. Am Surg. 1983 Jul;49(7):350–358. [PubMed] [Google Scholar]
  10. Frey C. F., Child C. G., Fry W. Pancreatectomy for chronic pancreatitis. Ann Surg. 1976 Oct;184(4):403–413. doi: 10.1097/00000658-197610000-00002. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Hart M. J., Miyashita H., Morita N., White T. T. Pancreaticojejunostomy. Report of a 25 year experience. Am J Surg. 1983 May;145(5):567–570. doi: 10.1016/0002-9610(83)90092-2. [DOI] [PubMed] [Google Scholar]
  12. Isaksson G., Ihse I. Pain reduction by an oral pancreatic enzyme preparation in chronic pancreatitis. Dig Dis Sci. 1983 Feb;28(2):97–102. doi: 10.1007/BF01315137. [DOI] [PubMed] [Google Scholar]
  13. Littenberg G., Afroudakis A., Kaplowitz N. Common bile duct stenosis from chronic pancreatitis: a clinical and pathologic spectrum. Medicine (Baltimore) 1979 Nov;58(6):385–412. doi: 10.1097/00005792-197911000-00001. [DOI] [PubMed] [Google Scholar]
  14. Little A. G., Moossa A. R. Gastrointestinal hemorrhage from left-sided portal hypertension. An unappreciated complication of pancreatitis. Am J Surg. 1981 Jan;141(1):153–158. doi: 10.1016/0002-9610(81)90029-5. [DOI] [PubMed] [Google Scholar]
  15. Longstreth G. F., Newcomer A. D., Green P. A. Extrahepatic portal hypertension caused by chronic pancreatitis. Ann Intern Med. 1971 Dec;75(6):903–908. doi: 10.7326/0003-4819-75-6-903. [DOI] [PubMed] [Google Scholar]
  16. Mercadier M., Clot J. P., Regensberg C. Les drainages et dérivations du canal de Wirsung dans le traitement des pancréatites chroniques. A propos de 115 observations. Ann Chir. 1968 Oct;22(21):1279–1284. [PubMed] [Google Scholar]
  17. Newton B. B., Rittenbury M. S., Anderson M. C. Extrahepatic biliary obstruction associated with pancreatitis. Ann Surg. 1983 Jun;197(6):645–653. doi: 10.1097/00000658-198306000-00002. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. PUESTOW C. B., GILLESBY W. J. Retrograde surgical drainage of pancreas for chronic relapsing pancreatitis. AMA Arch Surg. 1958 Jun;76(6):898–907. doi: 10.1001/archsurg.1958.01280240056009. [DOI] [PubMed] [Google Scholar]
  19. Prinz R. A., Aranha G. V., Greenlee H. B. Combined pancreatic duct and upper gastrointestinal and biliary tract drainage in chronic pancreatitis. Arch Surg. 1985 Mar;120(3):361–366. doi: 10.1001/archsurg.1985.01390270099017. [DOI] [PubMed] [Google Scholar]
  20. Prinz R. A., Greenlee H. B. Pancreatic duct drainage in 100 patients with chronic pancreatitis. Ann Surg. 1981 Sep;194(3):313–320. doi: 10.1097/00000658-198109000-00009. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Proctor H. J., Mendes O. C., Thomas C. G., Jr, Herbst C. A. Surgery for chronic pancreatitis. Drainage versus resection. Ann Surg. 1979 May;189(5):664–671. doi: 10.1097/00000658-197905000-00017. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Rignault D., Mine J., Moine D. Splenoportographic changes in chronic pancreatitis. Surgery. 1968 Apr;63(4):571–575. [PubMed] [Google Scholar]
  23. Sarles J. C., Nacchiero M., Garani F., Salasc B. Surgical treatment of chronic pancreatitis. Report of 134 cases treated by resection or drainage. Am J Surg. 1982 Sep;144(3):317–321. doi: 10.1016/0002-9610(82)90009-5. [DOI] [PubMed] [Google Scholar]
  24. Schulte W. J., LaPorta A. J., Condon R. E., Unger G. F., Geenen J. E., DeCosse J. J. Chronic pancreatitis: a cause of biliary stricture. Surgery. 1977 Sep;82(3):303–309. [PubMed] [Google Scholar]
  25. Scott J., Summerfield J. A., Elias E., Dick R., Sherlock S. Chronic pancreatitis: a cause of cholestasis. Gut. 1977 Mar;18(3):196–201. doi: 10.1136/gut.18.3.196. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Taylor R. H., Bagley F. H., Braasch J. W., Warren K. W. Ductal drainage or resection for chronic pancreatitis. Am J Surg. 1981 Jan;141(1):28–33. doi: 10.1016/0002-9610(81)90007-6. [DOI] [PubMed] [Google Scholar]
  27. Traverso L. W., Tompkins R. K., Urrea P. T., Longmire W. P., Jr Surgical treatment of chronic pancreatitis. Twenty-two years' experience. Ann Surg. 1979 Sep;190(3):312–319. doi: 10.1097/00000658-197909000-00006. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Wapnick S., Hadas N., Purow E., Grosberg S. J. Mass in the head of the pancreas in cholestatic jaundice: carcinoma or pancreatitis? Ann Surg. 1979 Nov;190(5):587–591. doi: 10.1097/00000658-197911000-00005. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Warshaw A. L. Conservation of pancreatic tissue by combined gastric, biliary, and pancreatic duct drainage for pain from chronic pancreatitis. Am J Surg. 1985 Apr;149(4):563–569. doi: 10.1016/s0002-9610(85)80057-x. [DOI] [PubMed] [Google Scholar]
  30. Warshaw A. L., Popp J. W., Jr, Schapiro R. H. Long-term patency, pancreatic function, and pain relief after lateral pancreaticojejunostomy for chronic pancreatitis. Gastroenterology. 1980 Aug;79(2):289–293. [PubMed] [Google Scholar]
  31. Warshaw A. L., Schapiro R. H., Ferrucci J. T., Jr, Galdabini J. J. Persistent obstructive jaundice, cholangitis, and biliary cirrhosis due to common bile duct stenosis in chronic pancreatitis. Gastroenterology. 1976 Apr;70(4):562–567. [PubMed] [Google Scholar]
  32. White T. T., Hart M. J. Pancreaticojejunostomy versus resection in the treatment of chronic pancreatitis. Am J Surg. 1979 Jul;138(1):129–134. doi: 10.1016/0002-9610(79)90252-6. [DOI] [PubMed] [Google Scholar]

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