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. 2025 Oct 10;23:1076. doi: 10.1186/s12967-025-07024-x

Table 2.

Analysis of basic characteristics between healthy and IBD patients in 16S rRNA cohort

16S rRNA Cohort Total (n = 57) Healthy (n = 19) IBD (n = 38) P
Sex, n(%) 1.000
Female 21 (36.84) 7 (36.84) 14 (36.84)
Male 36 (63.16) 12 (63.16) 24 (63.16)
Age, M (Q1, Q3) 41.00 (31.00, 49.00) 38.00 (30.00, 42.50) 43.00 (32.25, 53.50) 0.150
BMI, M (Q1, Q3) 22.66 (20.00, 24.88) 22.70 (20.59, 25.07) 22.54 (19.78, 24.19) 0.498
Albumin(g/L), Mean ± SD 36.63 ± 5.03 37.70 ± 4.98 34.50 ± 4.52 0.022*
Cholesterol (mmol/L), M (Q1, Q3) 4.00 (3.30, 4.70) 4.80 (4.35, 5.65) 3.60 (3.10, 4.07)  < .001*
White Blood Cells (× 103/μL), M (Q1, Q3) 6.63 (4.86, 8.43) 6.39 (5.27, 8.11) 6.71 (4.80, 8.56) 0.847
Erythrocyte Sedimentation Rate(mm/h), M (Q1, Q3) 15.46 (2.30, 35.93) 3.65 (1.53, 13.08) 45.94 (29.38, 50.62)  < .001*
CRP(mg/L), M (Q1, Q3) 4.04 (1.77, 9.69) 2.29 (1.27, 3.98) 13.31 (9.31, 15.59)  < .001*
Fecal Calprotectin(µg/g), M (Q1, Q3) 133.17 (72.71, 213.58) 84.12 (54.32, 139.06) 255.36 (181.57, 367.54)  < .001*

SD: standard deviation, M: Median, Q1: 1st Quartile, Q3: 3st Quartile