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. 2025 Oct 10;23:1076. doi: 10.1186/s12967-025-07024-x

Table 3.

Analysis of basic characteristics between healthy and IBD patients in RNA-seq cohort

RNA-seq Cohort Total (n = 73) Healthy (n = 19) IBD (n = 54) P
Sex, n(%) 0.492
Female 26 (35.62) 8 (42.11) 18 (33.33)
Male 47 (64.38) 11 (57.89) 36 (66.67)
Age, M (Q1, Q3) 38.00 (30.00, 51.00) 41.00 (33.50, 48.00) 33.50 (28.25, 51.50) 0.333
BMI, M (Q1, Q3) 22.14 (20.19, 25.24) 22.70 (20.59, 24.14) 22.08 (20.19, 25.53) 1.000
Albumin(g/L), Mean ± SD 37.86 ± 5.03 38.51 ± 5.16 36.02 ± 4.26 0.064
Cholesterol (mmol/L), M (Q1, Q3) 4.00 (3.20, 4.60) 4.90 (4.45, 5.60) 3.60 (3.10, 4.20)  < .001*
White Blood Cells (× 103/μL), M (Q1, Q3) 6.73 (4.97, 8.90) 6.01 (4.92, 8.36) 6.95 (5.09, 9.38) 0.285
Erythrocyte Sedimentation Rate(mm/h), M (Q1, Q3) 4.36 (1.64, 24.69) 3.04 (1.34, 5.42) 44.99 (26.66, 50.62)  < .001*
CRP(mg/L), M (Q1, Q3) 2.69 (1.27, 7.89) 1.76 (1.08, 3.24) 12.58 (9.70, 15.96)  < .001*
Fecal Calprotectin(µg/g), M (Q1, Q3) 89.28 (46.94, 168.82) 63.25 (36.29, 107.26) 255.36 (203.04, 342.90)  < .001*

SD: standard deviation, M: Median, Q1: 1st Quartile, Q3: 3st Quartile