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. 2025 Oct 10;25:1595. doi: 10.1186/s12903-025-06990-4

Table 2.

The median volume (mm3) of 3D facial imaging analysis at baseline (T0), 4 (T1), 8 (T2), and 12 (T3) weeks after the botulinum toxin injection

Area Volume [mm3, median (q1-q3)] p-value*
T0 T1 T2 T3
Left side

235,364

(219,078–269,013)

232,875

(214,548 − 263,442)

231,732

(215,273 − 261,103)

232,633

(213,779 − 263,688)

 0.002
Right side

238,900

(223,246–263,735)

235,786

(218,858 − 257,902)

232,110

(219,339 − 257,633)

232,647

(219,831 − 257,853)

 < 0.001
Both sides

481,030

(442,907 − 529,899)

470,490

(439,458–521,047)

473,433

(434,174–514,191)

467,572

(439,800 − 515,133)

 < 0.001

*Friedman’s statistical analysis and the significant level was taken at p < 0.05