TABLE 2.
MICs of β-lactams for A. baumannii AYE, E. coli DH10B(pTOPO-OXA-69), A. baumannii CIP 70.10(pAT-OXA-69), and A. baumannii BM4547(pAT-OXA-69) and reference strains E. coli DH10B, A. baumannii CIP 70.10, and A. baumannii BM4547
| β-Lactama | MIC (μg/ml) for strain:
|
|||||||
|---|---|---|---|---|---|---|---|---|
| A. baumannii AYE | E. coli DH10B (pTOPO-OXA-69) | E. coli DH10B | A. baumannii CIP 70.10 (pAT-OXA-69) | A. baumannii CIP 70.10 (pOXA-40)b | A. baumannii CIP 70.10 | A. baumannii BM4547 (pAT-OXA-69) | A. baumannii BM4547 | |
| Ampicillin | >512 | 16 | 4 | 64 | >256 | 32 | 64 | 64 |
| Ampicillin + CLA | >512 | 8 | 4 | 16 | >256 | 8 | 16 | 16 |
| Ticarcillin | >512 | 8 | 4 | 16 | >256 | 8 | 32 | 16 |
| Ticarcillin + CLA | 32 | 8 | 4 | 16 | >256 | 8 | 32 | 16 |
| Piperacillin | 256 | 4 | 2 | 16 | >256 | 16 | 16 | 16 |
| Piperacillin + TZB | 8 | 4 | 2 | 4 | >256 | 4 | 4 | 4 |
| Cephaloridine | >512 | 4 | 4 | >512 | >512 | >512 | >512 | >512 |
| Cephalothin | >512 | 4 | 4 | >512 | >512 | >512 | >512 | >512 |
| Cefuroxime | >512 | 4 | 4 | 64 | 64 | 64 | 64 | 64 |
| Ceftazidime | >512 | 0.06 | 0.06 | 2 | 4 | 2 | 4 | 4 |
| Cefotaxime | 512 | 0.06 | 0.06 | 8 | 16 | 8 | >32 | >32 |
| Cefepime | 512 | 0.06 | 0.06 | 1 | 2 | 1 | >32 | >32 |
| Cefpirome | 512 | 0.06 | 0.06 | 2 | 4 | 2 | >32 | >32 |
| Aztreonam | >512 | 0.06 | 0.12 | 64 | 64 | 64 | 64 | 64 |
| Imipenem | 1 | 0.06 | 0.06 | 0.5 | 4 | 0.5 | 1 | 1 |
| Meropenem | 1 | 0.06 | 0.06 | 0.5 | 4 | 0.5 | 1 | 1 |
a
CLA, clavulanic acid (2 μg/ml); TZB, tazobactam (4 μg/ml).
b
Data are from reference 14.