TABLE 4.

Comparison of amino acid sequences of the chromosome-encoded oxacillinases of A. baumannii isolates

A. baumannii strain(s)	OXA	Amino acid at class D β-lactamase positiona
		10	15	23	25	35	48	53	88	97	99	108	127	137	142	192	193	196	227	256	269	270	273
AYE, CH15, CH30	OXA-69	T	H	D	A	A	H	Q	A	D	E	N	A	K	V	Q	K	D	N	P	K	S	Q
CIP 70.10	OXA-64	—	—	E	G	—	—	—	—	—	Q	—	—	—	—	P	—	—	D	—	—	—	—
CLA-1, MK8560, BAR	OXA-66	—	—	V	—	—	—	—	—	—	K	—	—	—	—	—	—	—	—	—	—	—	—
CH13	OXA-71	—	—	E	—	—	—	—	—	—	Q	—	—	—	—	P	—	—	D	—	—	—	—
SDF	OXA-75	—	Y	E	—	—	—	H	—	—	Q	—	—	N	I	—	—	—	—	S	R	G	—
AMA-1	OXA-76	—	—	V	—	—	—	—	T	—	K	—	—	—	—	—	—	—	—	—	—	—	K
CIP7034T	OXA-77	S	—	E	—	—	—	—	—	—	Q	—	P	N	—	—	—	—	—	—	—	—	—
788b	OXA-51	—	—	E	—	V	Q	—	—	—	Q	D	—	—	—	P	—	—	D	—	—	—	—
884, 790c	OXA-65	—	—	E	—	—	Q	—	—	—	K	D	—	—	—	—	—	—	—	—	—	—	—
809c	OXA-68	—	—	E	—	—	Q	—	—	—	Q	N	—	N	—	—	E	—	—	—	—	—	—
812c	OXA-70	—	—	K	—	—	Q	—	—	N	Q	D	—	N	—	P	—	H	D	—	—	—	—

^aAmino acid residues that differed from the amino acid sequence of β-lactamase OXA-69 of A. baumannii AYE are indicated, whereas identical residues are shown by a dash.

^bStrain has been reported by Brown et al. (7).

^cStrains have been reported by Brown and Amyes (6).