TABLE 1.
Antimicrobial class and antimicrobial agent | MIC (μg/ml)
|
Relative resistancea | |
---|---|---|---|
E. coli KAM32/pUC18 | E. coli KAM32/pABE618 | ||
Aminoglycosides | |||
Kanamycin | 1 | 2 | 2 |
Gentamicin | 0.25 | 1 | 4 |
Quinolones | |||
Norfloxacin | 0.03 | 1 | 32 |
Ofloxacin | 0.015 | 0.06 | 4 |
Ciprofloxacin | <0.008 | 0.125 | 16 |
β-Lactam, imipenem | 0.25 | 0.25 | 1 |
Erythromycin | 4 | 8 | 2 |
Tetracycline | 0.5 | 0.5 | 1 |
Chloramphenicol | 1 | 2 | 2 |
Others | |||
SDSb | >128 | >128 | 1 |
DAPI | 0.5 | 8 | 16 |
TPPCl | 8 | 16 | 2 |
Triclosan | 0.5 | 2 | 4 |
Acriflavine | 2 | 32 | 16 |
Hoechst 33342 | 0.5 | 32 | 64 |
Daunorubicin | 4 | 64 | 16 |
Doxorubicin | 1 | 128 | 128 |
Trimethoprim | 0.125 | 0.25 | 2 |
Rhodamine 6G | 8 | 64 | 8 |
Ethidium bromide | 4 | 128 | 32 |
Relative resistance: MIC in E. coli harboring pABE618/MIC in E. coli harboring pUC18.
SDS, sodium dodecyl sulfate.