Skip to main content
. 2005 Oct;49(10):4344–4346. doi: 10.1128/AAC.49.10.4344-4346.2005

FIG. 2.

FIG. 2.

Efficacy of telavancin (TLV), vancomycin (VAN), and linezolid (LIN) in the murine pneumonia model. (A) Dosing initiated at 12 h postinoculation. Each group (at time of dosing) contained eight mice. The numbers of mice at time of harvest were two (control [CON]), seven (TLV, 40 mg/kg, i.v.), eight (TLV, 40 mg/kg, s.c.), seven (TLV, 20 mg/kg, s.c.), eight (VAN, 110 mg/kg, i.v.), and eight (LIN, 80 mg/kg, i.v.). (B) Dosing initiated at 24 h postinoculation. Each group (at time of dosing) contained eight mice. The numbers of mice at time of harvest were three (CON), eight (TLV, 40 mg/kg, i.v.), eight (TLV, 40 mg/kg, s.c.), seven (TLV, 20 mg/kg, s.c.), seven (VAN), and seven (LIN). The abscissa shows the time (h) postinoculation, and the ordinate shows the lung bacterial titer (log CFU/g). Arrows denote times of dosing. Data represent the mean ± 1 standard error of the mean. *, P < 0.05 versus pretreatment titer; #, P < 0.05 versus LIN; φ, P < 0.05 versus VAN.