FIG. 4.

Effect of treatment (Rx) with LBM415 on airway obstruction of mice inoculated with M. pneumoniae (Mp). Infected mice were treated with LBM415 or placebo daily for 13 days starting at 1 day after inoculation. Untreated controls were inoculated with sterile SP4. Airway obstruction was assessed by whole-body plethysmography by measuring Penh. Values shown are the means ± standard deviations (error bars). *, P < 0.05 005 between infected mice treated with LBM415 (n = 12) and infected mice treated with placebo (n = 12); **, P < 0.005 between infected mice treated with LBM415 (n = 12) and infected mice treated with placebo (n = 12). Values represent results from two independent experiments.