FIG. 5.

Effect of treatment (Rx) with LBM415 on airway hyperresponsiveness of mice inoculated with M. pneumoniae (Mp). Infected mice were treated with LBM415 or placebo daily for 13 days starting at 1 day after inoculation. Untreated controls were inoculated with sterile SP4. Airway hyperresponsiveness was assessed by whole-body plethysmography by measuring Penh after methacholine challenge. Values shown are the means ± standard deviations (error bars). *, P < 0.05 between infected mice treated with LBM415 (n = 12) and infected mice treated with placebo (n = 12). Values represent the results from two independent experiments.