TABLE 1.
Matrix of combinations of biofilm exposure to ciprofloxacin and ultrasound and P values for the COMSTAT “biomass” parameter for biofilms grown on various configurations compared with the negative control
| Hydrogel configuration | Ciprofloxacin exposure | Ultrasound application |
P value
|
||
|---|---|---|---|---|---|
| Day 1 | Day 2 | Day 3 | |||
| Experiment | + | + | 0.627 | 0.021a | <0.001a |
| Control for ultrasound only | − | + | 0.222 | 0.232 | 0.803 |
| Control for ciprofloxacin only | + | − | 0.219 | 0.332 | 0.602 |
| Negative controlb | − | − | |||
a
Significantly different result (P < 0.05).
b
Negative by ciprofloxacin exposure and ultrasound application.