TABLE 1.
DNA target | No. and type of isolates tested | No. of isolates with mutation | Nucleotide change | Amino acid change |
---|---|---|---|---|
katG codon 315 | 52 INHr | 31 | AGC→ACC | Ser315→Thr |
3 | AGC→ACA | Ser315→Thr | ||
52 INHs | 0 | |||
fabG1-inhA regulatory region | 52 INHr | 12 | −15C→T | |
1 | −17G→T | |||
52 INHs | 0 | |||
katG ORF | 5 INHr | 1 | GAC→GCC | Asp117→Ala |
1 | GGC→TGC | Gly491→Cys | ||
1 | ATG→TGC | Met257→Ile | ||
5 INHs | 0 | |||
inhA ORF | 5 INHr | 0 | ||
5 INHs | 0 |