FIG. 3.
Determination of MPC90 of PRA for clinical isolates of S. intermedius. Each graph represents total CFU (geometric mean ± standard deviation from triplicate experiments) recovered after 14 days of incubation; the curve of the least sensitive strain was omitted (see text). Representing the other veterinary FQs, MPC curves obtained with ENR (depicted for six representative strains) confirmed the higher potential of PRA also observed with control strains. The inoculum size was in the order of 5 × 109± 2 × 109 CFU per plate. Such bundles of curves may facilitate determination of a mean MPC plus a concentration range, which may be more characteristic for a species than MPC90.