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. 2025 Sep 16;647(8091):1063–1071. doi: 10.1038/s41586-025-09610-x

Fig. 3. Structure of activated hGluD2.

Fig. 3

a, Composite map of hGluD2 bound to d-serine, with the unsharpened map overlaid. b, Slice through the map in the subunit D and C LBD dimer to the d-serine-binding sites. c, Structural model of the d-serine binding site, with the local cryo-EM map overlaid. d, Model of the ion channel pore in the presence of d-serine, the A subunit is omitted for clarity (left) and rotated 90° (right) with all pore helices. e, Pore radius profile. The dashed line at 1.4 Å represents the radius of a water molecule.