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. 2025 Oct 15;25:3499. doi: 10.1186/s12889-025-24049-5

Table 3.

Linear mixed effect models for the associations of child abuse exposures with blood pressure over a 3-year follow-up period

Exposure variables Systolic blood pressure Diastolic blood pressure
p-interact (CA*baseline-rape-exposed) p-interact (CA*baseline-rape-exposed*time) B (se) p-value p-interact (CA*baseline-rape-exposed) p-interact (CA*baseline-rape-exposed*time) B (se) p-value
Any CA 0.455 0.579 −0.23 (0.31) 0.465 0.339 0.250 −0.35 (0.30) 0.245
Sexual CA 0.942 0.270 0.37 (0.57) 0.512 0.513 0.092 −0.38 (0.54) 0.481
Physical CA 0.625 0.376 −0.38 (0.32) 0.241 0.334 0.890 −0.32 (0.31) 0.298
Emotional CA 0.744 0.896 −0.11 (0.35) 0.974 0.081 0.687 −0.55 (0.33) 0.101
Parental neglect 0.196 0.511 −0.78 (0.38) 0.040 0.007 0.554 −0.94 (0.36) 0.009
Multiple CA 0.441 0.606 0.127 0.413 0.321 0.470
 0 Ref Ref
 1 0.350 0.632 −0.04 (0.39) 0.910 0.741 0.234 0.07 (0.37) 0.851
 2 0.450 0.891 −0.34 (0.45) 0.461 0.450 0.644 −0.51 (0.43) 0.239
 3 0.631 0.473 −0.36 (0.54) 0.507 0.120 0.601 −0.81 (0.51) 0.113
 4 0.201 0.725 −1.16 (1.18) 0.327 0.035 0.427 −2.08 (1.13) 0.065
Combined frequency and severity of childhood maltreatment
Sexual CA 0.894 0.286 0.404 0.536 0.114 0.692
 Never Ref Ref
 Some 0.771 0.359 0.46 (0.62) 0.461 0.511 0.242 −0.30 (0.59) 0.615
 Often 0.730 0.692 −0.026 (1.30) 0.984 0.671 0.718 −0.78 (1.25) 0.536
Physical CA 0.332 0.351 0.102 0.296 0.656 0.915
 Never Ref Ref
 Some 0.637 0.334 −0.55 (0.39) 0.161 0.544 0.995 −0.17 (0.37) 0.644
 Often 0.210 0.842 −0.165 (0.42) 0.697 0.330 0.188 −0.50 (0.40) 0.217
Emotional CA 0.661 0.799 0.622 0.185 0.836 0.591
 Never Ref Ref
 Some 0.906 0.929 0.14 (0.42) 0.742 0.040 0.729 −0.59 (0.40) 0.143
 Often 0.792 0.381 −0.27 (0.53) 0.611 0.565 0.524 −0.49 (0.50) 0.328
Parental neglect 0.084 0.594 0.462 0.011 0.472 0.286
 Never Ref Ref
 Some 0.968 0.666 −0.75 (0.43) 0.081 0.029 0.422 −0.71 (0.41) 0.082
 Often 0.033 0.656 −0.89 (0.69) 0.201 0.035 0.830 −1.62 (0.66) 0.014
Severity score
 CA severity score 0.919 0.370 −0.031 (0.05) 0.432 0.144 0.268 −0.035 (0.04) 0.188
 Sexual CA score 0.915 0.219 0.16 (0.19) 0.416 0.545 0.102 −0.32 (0.39) 0.422
 Physical CA score 0.201 0.782 −0.10 (0.10) 0.335 0.319 0.896 −0.06 (0.09) 0.556
 Emotional CA score 0.613 0.403 −0.07 (0.11) 0.520 0.445 0.681 −0.12 (0.11) 0.261
 Parental neglect score 0.187 0.413 −0.15 (0.15) 0.311 0.050 0.845 −0.24 (0.14) 0.097

B: beta co-efficient of linear mixed effect model. Models adjusted for age at baseline, employment, education, current smoking, current alcohol use and baseline rape-exposure. CA, childhood abuse. P-interact (CA*baseline-rape-exposed): p-value for the interaction terms, child abuse*baseline-rape-exposed, in each exposure type and outcome examined