Table 4.
Linear mixed effect models for the associations of childhood abuse exposures with total cholesterol and glycated haemoglobin over a 3-year follow-up period
| Exposure variables | Total cholesterol | Glycated haemoglobin | ||||||
|---|---|---|---|---|---|---|---|---|
| p-interact (CA*baseline-rape-exposed) | p-interact (CA*baseline-rape-exposed*time) | B (se) | p-value | p-interact (CA*baseline-rape-exposed) | p-interact (CA*baseline-rape-exposed*time) | B (se) | p-value | |
| Any CA | 0.707 | 0.039 | −0.01 (0.03) | 0.692 | 0.629 | 0.181 | 0.01 (0.02) | 0.974 |
| Sexual CA | 0.790 | 0.797 | −0.05 (0.05) | 0.356 | 0.723 | 0.383 | 0.02 (0.03) | 0.656 |
| Physical CA | 0.412 | 0.287 | 0.01 (0.03) | 0.774 | 0.333 | 0.099 | −0.01 (0.02) | 0.934 |
| Emotional CA | 0.168 | 0.849 | −0.09 (0.04) | 0.008 | 0.795 | 0.781 | 0.01 (0.02) | 0.992 |
| Parental neglect | 0.736 | 0.121 | 0.01 (0.04) | 0.818 | 0.179 | 0.408 | −0.04 (0.02) | 0.107 |
| Multiple CA type | 0.239 | 0.196 | 0.522 | 0.076 | 0.387 | 0.143 | ||
| 0 | Ref | Ref | ||||||
| 1 | 0.469 | 0.094 | 0.01 (0.04) | 0.833 | 0.233 | 0.707 | 0.03 (0.02) | 0.253 |
| 2 | 0.144 | 0.095 | 0.01 (0.05) | 0.956 | 0.522 | 0.622 | −0.04 (0.02) | 0.219 |
| 3 | 0.045 | 0.545 | −0.06 (0.05) | 0.307 | 0.567 | 0.162 | −0.03 (0.03) | 0.343 |
| 4 | 0.377 | 0.757 | −0.19 (0.12) | 0.113 | 0.067 | 0.659 | 0.12 (0.07) | 0.099 |
| Combined frequency and severity of childhood abuse | ||||||||
| Sexual CA | 0.556 | 0.825 | 0.179 | 0.433 | 0.539 | 0.937 | ||
| Never | Ref | Ref | ||||||
| Some | 0.663 | 0.878 | −0.10 (0.065) | 0.113 | 0.576 | 0.569 | 0.01 (0.03) | 0.925 |
| Often | 0.093 | 0.180 | 0.17 (0.14) | 0.214 | 0.173 | 0.501 | 0.07 (0.08) | 0.373 |
| Physical CA | 0.575 | 0.086 | 0.264 | 0.564 | 0.068 | 0.607 | ||
| Never | Ref | Ref | ||||||
| Some | 0.456 | 0.203 | 0.01 (0.04) | 0.983 | 0.199 | 0.098 | 0.01 (0.02) | 0.909 |
| Often | 0.602 | 0.342 | 0.02 (0.04) | 0.645 | 0.798 | 0.921 | −0.01 (0.02) | 0.786 |
| Emotional CA | 0.242 | 0.971 | 0.013 | 0.589 | 0.998 | 0.986 | ||
| Never | Ref | Ref | ||||||
| Some | 0.186 | 0.954 | −0.08 (0.04) | 0.046 | 0.743 | 0.884 | −0.01 (0.02) | 0.591 |
| Often | 0.401 | 0.833 | −0.11 (0.05) | 0.037 | 0.375 | 0.874 | 0.03 (0.03) | 0.451 |
| Parental neglect | 0.605 | 0.191 | 0.967 | 0.569 | 0.453 | 0.567 | ||
| Never | Ref | Ref | ||||||
| Some | 0.630 | 0.167 | 0.02 (0.04) | 0.710 | 0.047 | 0.384 | −0.06 (0.02) | 0.017 |
| Often | 0.145 | 0.320 | −0.08 (0.07) | 0.240 | 0.485 | 0.659 | 0.03 (0.04) | 0.410 |
| Severity score | ||||||||
| CA severity score | 0.804 | 0.382 | −0.01 (0.01) | 0.269 | 0.621 | 0.335 | −0.01 (0.01) | 0.230 |
| Sexual CA score | 0.385 | 0.292 | −0.05 (0.02) | 0.024 | 0.506 | 0.935 | −0.01 (0.01) | 0.714 |
| Physical CA score | 0.509 | 0.068 | 0.01 (0.01) | 0.449 | 0.593 | 0.146 | −0.01 (0.01) | 0.503 |
| Emotional CA score | 0.235 | 0.850 | −0.01 (0.01) | 0.032 | 0.287 | 0.968 | −0.01 (0.01) | 0.929 |
| Parental neglect score | 0.849 | 0.551 | −0.01 (0.01) | 0.825 | 0.892 | 0.379 | −0.01 (0.01) | 0.436 |
B: beta co-efficient of linear mixed effect model. Models adjusted for age at baseline, employment, education, current smoking, current alcohol use and baseline rape-exposure. CA, childhood abuse. P-interact (CA*baseline-rape-exposed): p-value for the interaction terms (CA*baseline-rape-exposed) in each exposure type and outcome examined