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. 2025 Oct 14;25:493. doi: 10.1186/s12871-025-03343-0

Table 2.

Results for primary outcomes according to combinations of surgery type and SAPB type

Subgroup No. of studies and patients I2, % MD (95%CI) P
Breast surgery + DSAPB
 TFAR 6 (179/179) 96.9 0.01 (−1.41 to 1.42) 0.991
 24-h TAC 5 (114/120) 89.3 −0.40 (−2.79 to 1.98) 0.740
 24-h pain scores at rest 4 (124/124) 83.5 0.02 (−0.62 to 0.67) 0.942
Breast surgery + SSAPB
 TFAR 3 (94/94) 9.0 −1.55 (−1.81 to −1.29)  < 0.001
 24-h TAC 3 (94/94) 83.4 2.11 (1.18 to 3.04)  < 0.001
 24-h pain scores at rest 1 (25/25) NA −0.56 (−1.17 to 0.05) 0.073
Thoracic surgery + DSAPB
 TFAR 2 (71/71) 94 −3.69 (−10.64 to 3.26) 0.298
 24-h TAC 1 (31/31) NA 1.26 (0.27 to 2.25) 0.013
 24-h pain scores at rest 4 (125/114) 62.4 −0.24 (−0.74 to 0.25) 0.332
Thoracic surgery + SSAPB
 TFAR 7 (244/241) 98.3 −0.41 (−2.40 to 1.58) 0.687
 24-h TAC 4 (123/122) 75.9 4.02 (2.55 to 5.49)  < 0.001
 24-h pain scores at rest 10 (325/314) 92.2 0.34 (−0.10 to 0.78) 0.126

DSAPB Deep serratus anterior plane block, MD Mean difference, NA Not applicable, SSAPB Superficial serratus anterior plane block, TAC Total analgesic consumption in intravenous morphine equivalents, TFAR Time to first analgesia request, TPVB Thoracic paravertebral block