Table 1.
Demographic, clinical characteristics, and pro-inflammatory cytokines of participants.
| Variables | AD (n = 43) | NAD (n = 68) | HC (n = 53) | T/F/χ2 | p-values |
|---|---|---|---|---|---|
| Age (years) | 30.91±9.76 | 28.25±7.06 | 31.23±9.09 | 2.23 | 0.245a |
| Sex (male/female) | 14/29 | 17/51 | 21/32 | 2.96 | 0.228b |
| Education (years) | 15.81±2.17 | 16.03±2.21 | 15.57±2.28 | 0.65 | 0.525c |
| Mean FD | 0.07±0.05 | 0.07±0.06 | 0.08±0.07 | 0.13 | 0.875c |
| 17-item HAMD score | 23.51±4.32 | 19.54±3.32 | N/A | 5.45 | <0.001d |
| Anxiety/somatization | 8.35±1.23 | 4.40±1.39 | N/A | 15.20 | <0.001d |
| Log IL-1β (log10 pg/ml) | 1.26±0.64 | 1.17±0.50 | 1.06±0.33 | 0.74 | 0.692a |
| Log IL-6 (log10 pg/ml) | 1.67±0.74 | 1.52±0.59 | 1.28±0.43 | 9.73 | 0.008a |
| Log TNF-α (log10 pg/ml) | 2.39±0.56 | 2.35±0.45 | 2.22±0.41 | 1.70 | 0.185c |
Abbreviations: AD, anxious depression; NAD, non-anxious depression; HC, healthy controls; FD, framewise displacement; HAMD, Hamilton Rating Scale for Depression; IL, Interleukin; TNF, Tumor Necrosis Factor.
Kruskal-Wallis test.
Chi-square test.
One-way ANOVA.
Two-sample t-test.