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. 2025 Oct 15;5:64. doi: 10.1186/s44158-025-00285-4

Table 4.

Mixed linear regression outcomes for Crs and different PEEP levels and supine vs prone position

Crs Cdyn PIP PPLAT ΔP
Coeff P values 95% CI Coeff P values 95% CI Coeff P values 95% CI Coeff P values 95% CI Coeff P values 95% CI
Position
 Prone − 0.14 < 0.001 − 0.17; − 0.10 − 0.04 < 0.001 − 0.06; − 0.02 1.47 < 0.001 1.11;1.83 1.35 < 0.001 1.05;1.64 1.31 < 0.001 1.01; 1.62
PEEP (cmH2O)
 5 0.06 0.001 0.02; 0.10 0.044 < 0.001 0.02; 0.06 3.84 < 0.001 3.42;4.26 4.03 < 0.001 3.68; 4.38 −0.84 < 0.001 − 1.20; − 0.49
 10 0.08 < 0.001 0.04; 0.13 0.049 < 0.001 0.02; 0.07 8.38 < 0.001 7.92;8.83 8.42 < 0.001 8.05–8.80 −1.46 < 0.001 − 1.85; − 1.08
 Comorb − 0.03 0.488 − 0.15; 0.07 − 0.07 0.064 − 0.14; 0.02 1.87 0.009 0.46; 3.27 0.63 0.184 − 0.30; 1.58 0.59 0.223 − 0.36; 1.55

Prone position coefficient is referred to supine position; PEEP 5 and 10 are referred to ZEEP. Crs static respiratory system compliance, PEEP positive end-expiratory pressure, PIP peak inspiratory pressure, PPLAT plateau pressure, ZEEP zero end-expiratory pressure, ΔP driving pressure