Table 4.
Mixed linear regression outcomes for Crs and different PEEP levels and supine vs prone position
| Crs | Cdyn | PIP | PPLAT | ΔP | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Coeff | P values | 95% CI | Coeff | P values | 95% CI | Coeff | P values | 95% CI | Coeff | P values | 95% CI | Coeff | P values | 95% CI | |
| Position | |||||||||||||||
| Prone | − 0.14 | < 0.001 | − 0.17; − 0.10 | − 0.04 | < 0.001 | − 0.06; − 0.02 | 1.47 | < 0.001 | 1.11;1.83 | 1.35 | < 0.001 | 1.05;1.64 | 1.31 | < 0.001 | 1.01; 1.62 |
| PEEP (cmH2O) | |||||||||||||||
| 5 | 0.06 | 0.001 | 0.02; 0.10 | 0.044 | < 0.001 | 0.02; 0.06 | 3.84 | < 0.001 | 3.42;4.26 | 4.03 | < 0.001 | 3.68; 4.38 | −0.84 | < 0.001 | − 1.20; − 0.49 |
| 10 | 0.08 | < 0.001 | 0.04; 0.13 | 0.049 | < 0.001 | 0.02; 0.07 | 8.38 | < 0.001 | 7.92;8.83 | 8.42 | < 0.001 | 8.05–8.80 | −1.46 | < 0.001 | − 1.85; − 1.08 |
| Comorb | − 0.03 | 0.488 | − 0.15; 0.07 | − 0.07 | 0.064 | − 0.14; 0.02 | 1.87 | 0.009 | 0.46; 3.27 | 0.63 | 0.184 | − 0.30; 1.58 | 0.59 | 0.223 | − 0.36; 1.55 |
Prone position coefficient is referred to supine position; PEEP 5 and 10 are referred to ZEEP. Crs static respiratory system compliance, PEEP positive end-expiratory pressure, PIP peak inspiratory pressure, PPLAT plateau pressure, ZEEP zero end-expiratory pressure, ΔP driving pressure