ADME	Absorption, distribution, metabolism, and excretion
AIF	Apoptosis-inducing factor
AKT	Serine/threonine kinase (also known as protein kinase B, PKB)
AMPK	AMP-activated protein kinase
AP-1	Activator protein 1
Bak	Bcl-2 homologous antagonist/killer
Bax	Bcl-2–associated X protein
Bcl-xL	B-cell lymphoma-extra large
Bcl-2	B-cell lymphoma 2
Bid	BH3-interacting domain death agonist
CDK2	Cyclin-dependent kinase 2
CETSA	Cellular thermal shift assay
c-Myc	Cellular myelocytomatosis oncogene
DARTS	Drug affinity responsive target stability
EGFR	Epidermal growth factor receptor
EMT	Epithelial–mesenchymal transition
ERK	Extracellular signal-regulated kinase
FasL	Fas ligand
FYN	Proto-oncogene tyrosine-protein kinase Fyn
HIF-1α	Hypoxia-inducible factor-1 alpha
HRAS	Harvey rat sarcoma viral oncogene homolog
HSP90AA1	Heat shock protein 90 alpha family class A member 1
IκBα	Inhibitor of nuclear factor kappa-B alpha
IL-6	Interleukin-6
iNOS	Inducible nitric oxide synthase
JAK	Janus kinase
JNK	c-Jun N-terminal kinase
LPS	Lipopolysaccharide
MDR1	Multidrug resistance protein 1
MAPK	Mitogen-activated protein kinase
mTOR	Mechanistic target of rapamycin
MYC	Myelocytomatosis oncogene
NF-κB	Nuclear factor kappa-light-chain-enhancer of activated B cells
Nrf2	Nuclear factor erythroid 2–related factor 2
PAMPA	Parallel artificial membrane permeability assay
PARP	Poly(ADP-ribose) polymerase
PD-L1	Programmed death-ligand 1
PDX	Patient-derived xenografts
PIK3CA	Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1
PI3K	Phosphoinositide 3-kinase
PPI	Protein–protein interaction
PTGS2 (COX-2)	Prostaglandin-endoperoxide synthase 2 (cyclooxygenase-2)
RHOA	Ras homolog family member A
RIP1	Receptor-interacting protein kinase 1
ROS	Reactive oxygen species
SIRT1	Sirtuin 1
STAT3	Signal transducer and activator of transcription 3
TNF	Tumor necrosis factor
u-PA	Urokinase-type plasminogen activator
VEGF	Vascular endothelial growth factor
Wnt	Wingless-related integration site