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. 2025 Sep 24;14(19):6758. doi: 10.3390/jcm14196758
CVD Cardiovascular Diseases
T2DM Type 2 Diabetes Mellitus
GLP-1 Glucagon-Like Peptide-1
GIP Glucose-Dependent Insulinotropic Polypeptide
CVOTs Cardiovascular Outcome Trials
MACE Major Adverse Cardiovascular Events
MI Myocardial Infarction
HFpEF Heart Failure with Preserved Ejection Fraction
ASCVD Atherosclerotic Cardiovascular Disease
VSMCs Vascular Smooth Muscle Cells
LDL-C Low-Density Lipoprotein Cholesterol
HDL-C High-Density Lipoprotein Cholesterol
MMP-9 Matrix Metalloproteinase-9
MCP-1 Monocyte Chemoattractant Protein-1
LDLR Low-Density Lipoprotein Receptor
cAMP Cyclic Adenosine Monophosphate
NF-κB Nuclear Factor Kappa-B
MAPK Mitogen-Activated Protein Kinase
VCAM-1 Vascular Cell Adhesion Molecule-1
ICAM-1 Intercellular Adhesion Molecule-1
ATP Adenosine Triphosphate
ABCA1 ATP-Binding Cassette Transporter A1
eNOS endothelial Nitric Oxidase Synthase
NO Nitric Oxide
SBP Systolic Blood Pressure
PAI-1 Plasminogen Activator Inhibitor-1
BBB Blood-Brain Barrier
TNF-α Tumor Necrosis Factor Alpha
IL-6 Interleukin 6
IL-1β Interleukin 1 Beta
hs-CRP High-Sensitivity C-Reactive Protein
NLRP3 NOD-, LRR-, and Pyrin Domain-Containing Protein 3
PI3K Phosphatidylinositol 3-kinase (PI3K)
ROS Reactive Oxygen Species
MnSOD Manganese Superoxide Dismutase
GPx-1 Glutathione Peroxidase-1
Nrf2 Nuclear Factor Erythroid 2-related Factor 2
ARE Enhanced Antioxidant Response
NADPH Nicotinamide Adenine Dinucleotide Phosphate
NOX NADPH Oxidase
TGF-β Transforming Growth Factor Beta
CBF Cerebral Blood Flow
BDNF Brain-Derived Neurotrophic Factor
KCCQ Kansas City Cardiomyopathy Questionnaire
CKD Chronic Kidney Disease
HFrEF Heart Failure with Reduced Ejection Fraction
LVEF Left Ventricular Ejection Fraction
VEGF Vascular Endothelial Growth Factor
SOD Superoxide Dismutase