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. 2025 Oct 1;14(19):6959. doi: 10.3390/jcm14196959
ACL Anterior Cruciate Ligament
PRP Platelet-Rich Plasma
PRF Platelet-Rich Fibrin
BMAC Bone Marrow Aspirate Concentrate
MSC Mesenchymal Stem Cell
EVs Extracellular Vesicles
ADSCs Adipose-Derived Stem Cells
ADRCs Adipose-Derived Regenerative Cells
MRI Magnetic Resonance Imaging
US Ultrasound
UTE-T2* Ultrashort Echo Time T2-star (advanced MRI mapping sequence)
T2* T2-star relaxation time (MRI parameter sensitive to tissue microstructure and field inhomogeneity)
CRISPR-Cas9 Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated protein 9 (gene editing tool)
RCT Randomized Controlled Trial
IKDC International Knee Documentation Committee score
KOOS Knee Injury and Osteoarthritis Outcome Score
Lysholm Lysholm Knee Scoring Scale
PROs Patient Reported Outcomes
DBM Demineralized Bone Matrix
LP-PRP Leukocyte-Poor Platelet Rich Plasma
LR-PRP Leukocyte-Rich Platelet Rich Plasma
BLA Biologics License Application
FDA U.S. Food and Drug Administration
HCT/P Human Cells, Tissues, and Cellular and Tissue-Based Products
VEGF Vascular Endothelial Growth Factor
PDGF Platelet-Derived Growth Factor
TGF-β Transforming Growth Factor Beta
IL-1β Interleukin-1 Beta
TNF-α Tumor Necrosis Factor Alpha
MMPs Matrix Metalloproteinases
TIMP-1 Tissue Inhibitor of Metalloproteinase-1