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. 2025 Sep 28;17(19):3085. doi: 10.3390/nu17193085
1-κB⍺ I kappaB alpha
4-OHT 4-hydroxytamoxifen
5-FU 5-fluorouracil
AMPK AMP-activated protein kinase
APCs Antigen-presenting cells
ATF4 Activating transcription factor 4
β-carotene Beta-carotene
Bax Bcl-2-associated X protein
Bcl B-cell lymphoma
Bid BH3-interacting domain death agonist
Ca2+ Calcium
ccRCC Clear cell renal cell carcinoma
CDK Cyclin-dependent kinase
CHOP C/EBP homologous protein
CML Chronic myeloid leukaemia
CRC Colorectal cancer
CRT Calreticulin
CSCs Cancer stem cells
CTL Cytotoxic T lymphocytes
DAMPs Damage-associated molecular patterns
DC Dendritic cells
DISC Death-inducing signalling complex
DNases Deoxyribonucleases
DR Death receptor
DX Doxorubicin
EGFR Epidermal growth factor receptor
EMT Epithelial–mesenchymal transition
ER Endoplasmic reticulum
ER+ Oestrogen receptor–positive
ER Oestrogen receptor–negative
ERK Extracellular signal-regulated kinase
ESCC Oesophageal squamous cell carcinoma
ESM1 Endothelial cell specific molecule 1
FADD Fas-associated death domain
FASL Fas ligand
Fe2+ Ferrous iron
FPE First-pass effect
GC Gastric cancer
GOT-1 Glutamic-oxaloacetic transaminase 1
GPER G protein-coupled oestrogen receptor
GRP78 Glucose-regulated protein 78
GSDME Gasdermin E
GTPBP4 Guanosine triphosphate binding protein 4
HCC Hepatocellular carcinoma
HDAC Histone deacetylase
HIF-1α Hypoxia-inducible factor 1-alpha
HMOX1 Heme oxygenase 1
HNSCC Head and neck squamous cell carcinomas
HPLC High-performance liquid chromatography
HSCCC High-speed counter-current chromatography
ICD Immunogenic cell death
IHC Immunohistochemistry
IR Ionising radiation
IV Intravenous
JNK c-Jun N-terminal kinase
KM Kunming
KRAS Kirsten rat sarcoma virus
lncRNAs Long non-coding RNAs
MAE Microwave-assisted extraction
MAPK Mitogen-activated protein kinase
MitoROS Mitochondrial ROS
MLKL Mixed lineage kinase domain-like protein
MM Multiple myeloma
MMP Mitochondrial membrane potential
MMP-2 Matrix metalloproteinase-2
MMP-9 Matrix metalloproteinase-9
MS Murashige and Skoog
NF-κB Nuclear factor kappa B
NHE1 Sodium–hydrogen exchanger 1
NSCLC Non-small cell lung cancer
OSCC Oral squamous cell carcinoma
OXA Oxaliplatin
PAK1 p21-activated kinase 1
PAMPs Pathogen-associated molecular patterns
PARP Poly (ADP-ribose) polymerase
PBMC Patient peripheral blood mononuclear cell
PCD Programmed cell death
PDK1 Pyruvate dehydrogenase kinase 1
PFKFB2 6-phosphofruto-2-kinase/fructose-2,6-biphosphate
PHD3 Prolyl hydroxylase 3
PKM2 Pyruvate kinase isoform M2
PTEN Phosphatase and tensin homologue
PUMA p53 upregulated modulator of apoptosis
PYCR1 Pyrroline-5-carboxylate reductase 1
rhApo2L/TRAIL Apo2 ligand/tumour necrosis factor-related apoptosis-inducing ligand
RIPK1 Receptor-interacting protein kinase1
RIPK3 Receptor-interacting protein kinase3
ROS Reactive oxygen species
RT-PCR Real-time polymerase chain reaction
SC-CO2 Supercritical carbon dioxide
SCLC Small cell lung cancer
SD Sprague Dawley
STP Sarcoma-targeting-peptide
TAM Tamoxifen
TCM Traditional Chinese Medicine
TGF-β Transforming growth factor β
TIME Tumour immune microenvironment
TLRs Toll-like receptors
TME Tumour microenvironment
TNBC Triple negative breast cancer
TNFα Tumour necrosis factor-α
TRAP1 Tumour necrosis factor receptor-associated protein 1
Tregs Regulatory T Cells
TrxR1 Thioredoxin reductase 1
UAE Ultrasonic-assisted extraction
XBP-1 X-box binding protein 1
Zn-SHK-PEG Zinc-shikonin-polyethylene glycol