SDs	Sleep disorders
MDD	Major depressive disorder
TCAs	Tricyclic drugs
5-HT	Serotonin
SSRIs	Selective Serotonin Reuptake Inhibitor(s)
NE	Norepinephrine
SNRI	Serotonin–norepinephrine reuptake inhibitors
DXT	Duloxetine
DVS	Desvenlafaxine succinate
GAD	Generalized Anxiety Disorder
SAD	Social Anxiety Disorder
PTSD	Post-traumatic stress disorder
OCD	Obsessive–compulsive disorder
PSD	Post-stroke depression
CGA	Chlorogenic acid
FA	Ferulic acid
CA	Caffeic acid
DA	Dopamine
PFC	Prefrontal Cortex
A1R	A1 receptors
A2AR	A2A receptors
ACTH	adrenocorticotropic hormone
DMN	Default mode network
MAO-A	Monoamine oxidase-A
DSM-IV	Diagnostic and Statistical Manual of Mental Disorders-IV
SPT	Sugar preference test
FST	Forced swim test
TST	Tail suspension test
OFT	Open field test
IL-6	Interleukin-6
TNF-α	Tumor necrosis factor-α
SOD	Superoxide dismutase
GPx	Glutathione peroxidase
PDD	Postpartum Depression
IDO	Indoleamine 2, 3-dioxygenase
LPS	Lipopolysaccharide
UA	Uric acid
3-HK	3-Hydroxykynurenine
KYN	Kynurenine
KP	Kynurenine pathway
CNS	Central Nervous System
CUS	Chronic unpredictable stress
LTP	Long-term potentiation
CORT	Corticosterone
MAPK	Mitogen-activated protein kinase
ERK	Extracellular regulated protein kinases
NF-κB	Nuclear Factor kappa-light-chain-enhancer of activated B cells
CWIRS	Chronic water immersion restraint stress
CMS	Chronic Mild Stress
PGC-1α	Peroxisome proliferators-activated receptor γ coactivator lα
KAT	Kynurenine aminotransferase
KYNA	Kynurenic acid
SRS	Stress-induced stress
PGE2	Prostaglandin E2
BrdU	Bromodeoxyuridine
DCX	Doublecortin
IL-1β	Interleukin-1β
SNAP-25	Synaptosomal-Associated Protein 25
IFN-γ	Interferon-gamma
MDA	Malondialdehyde
BDNF	Brain-derived neurotrophic factor
GSH	Glutathione
GR	Glucocorticoid receptor
ADRA1A	α1Aadrenoreceptor
TBARS	Thiobarbituric acid reactive substances
AChE	Acetylcholinesterase
OS	Oxidative stress
Nrf2	Nuclear factor-erythroid 2 related factor 2
EPM	Elevated plus maze test
LDB	Light/dark box test
IAT	Inhibitory avoidance test
FET	Free exploration test
PNS	Peripheral nervous system
MWM	Morris water maze
MBT	Marble burying test
5-HTP	5-Hydroxytryptophan
REM	Rapid eye movement sleep
NREM	Non-rapid eye movement sleep
Per1/Per2	Period Circadian Regulator 1/2
α1-AR	α1-adrenergic receptor
iTBS	Intermittent burst theta stimulation
dmPFC	Dorsomedial prefrontal cortex
SBP	Systolic Blood Pressure
DBP	Diastolic Blood Pressure
CR	Circadian Rhythm
EEG	Electroencephalogram
ICCA	Isochlorogenic acid
SYG	Syringaresinol-di-O-glucoside
GSK-3β	Glycogen synthase kinase-3β
OAB	Overactive bladder
CSF	Cerebrospinal fluid
SCN	Suprachiasmatic nucleus
CREB	Cyclic-AMP response binding protein
OXRs	Orexin receptor antagonists
NMDA	N-methyl-d-aspartate
PKC	Protein kinase C
cAMP	Cyclic adenosine monophosphate
LS	Lateral septal
SNP	Single nucleotide polymorphism
PAG	Periaqueductal gray
mPFC	Medial prefrontal cortex
AANAT	Aryl alkylamine N-acetyltransferase
CRTC1	CREB-regulated transcription coactivator 1
CRE	cAMP response element
PI3K	Phosphatidylinositol 3-kinase
mTOR	Mechanistic target of rapamycin
TrkB	Tropomyosin-related kinase B
PLC-γ	Phospholipase C-γ
AMPAR	α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor
NAc	Nucleus accumbens
IRS2	Insulin receptor substrate 2
CAFLTP	Caffeine-induced LTP
P-CaMKII	Phosphorylated calcium calmodulin kinase I
GABA	Gamma-aminobutyric acid
CCK	Cholecystokinin
AvBNST	Anteroventral nucleus of the bed nucleus of the stria terminalis
VTA	Ventral tegmental area
DRN	Dorsal raphe nucleus
BLA	Basal lateral amygdala
ROS	Reactive oxygen species
HPA axis	hypothalamic–pituitary–adrenal axis
GCs	Glucocorticoids
H2O2	Hydrogen peroxide
·OH	Hydroxyl radicals
ROO·	Peroxyl radicals
1O2	Singlet oxygen
JNK1/2	c-Jun N-terminal kinase 1/2
CCL2	C-C motif chemokine ligand-2
CRP	C-reactive protein
TDO	Tryptophan 2,3-dioxygenase
NKA	Na+/K+-ATPase
IκBα	Inhibitor of nuclear factor kappa-Bα
CRH	Corticotropin releasing hormone
CAR	Cortisol awakening response
CRF	Corticotrophin releasing factor
MRs	Mineralocorticoid receptors
MGB axis	Microbiota-Gut–Brain axis
SCFAs	Short-chain fatty acids
HIF-1	Hypoxia-inducible factor-1
CUMS	Chronic unpredictable mild stress
FMT	Fecal microbiota transplantation
4EPS	4-Ethylphenyl sulfate
MP	Muramyl peptides
EC	Enterochromaffin cells