Table I. Comparison of gene induction in 2fEgΔBY440 cells in response to IFN-γ or Epo.
| Fold induction (6 h stimulation) |
Fold induction (18 h stimulation) |
||||
|---|---|---|---|---|---|
| Gene namea | IFN-γ | Epo | Gene namea | IFN-γ | Epo |
| GBP-1 | 10.98 | 5.87 | GBP-1 | 17.5 | 12.72 |
| HLA-Eb | 5.54 | 3.04 | RING12 | 11.46 | 7.96 |
| TAP1 | 4.69 | 3.81 | Ubiquitin-conjugating enzyme | 9.55 | 5.52 |
| IL-15Rαc | 4.54 | 3.55 | TAP1 | 8.98 | 6.29 |
| 248145 | 4.34 | 2.33 | IL-15Rαc | 7.42 | 6.63 |
| RING12 | 4.04 | 2.66 | HLA-Eb | 7.41 | 4.62 |
| HLA-Eb | 3.89 | 3.18 | CIITA | 6.79 | 3.86 |
| 240703 | 3.24 | 2.75 | 248145 | 5.9 | 4.25 |
| NKC4 | 2.94 | 1.79 | NKC4 | 5.84 | 3.68 |
| CIITA | 2.75 | 2.78 | IFP-53b | 5 | 3.36 |
| Auto Ag SS-A/Ro | 2.72 | 2.46 | STAT1 | 4.74 | 3.51 |
| 364744 | 2.64 | 1.91 | Prot. C13/RING 10 | 4.67 | 4.02 |
| Ubiquitin-conjugating enzyme | 2.63 | 2.28 | MHC I Ag B27 | 4.62 | 4.5 |
| Transthyretin | 2.49 | 1.9 | IFP-53b | 4.55 | 3.55 |
| 247050 | 2.26 | 2.03 | LMP2 | 4.36 | 3.32 |
| 214342 | 2.16 | 1.8 | 247050 | 4.3 | 3.24 |
| Caspase 7 | 2.09 | 2.23 | 240703 | 4.28 | 4.26 |
| STAT1 | 2.07 | 2.69 | RING4 | 4.08 | 2.57 |
| IFP-53b | 2.05 | 2.21 | IP-30 | 4.06 | 2.17 |
| IFP-53b | 2.04 | 2.33 | HLA-Eb | 3.78 | 3.7 |
| IP-30 | 2 | 2.13 | Caspase 8/FLICE/MACH | 3.6 | 2.97 |
| Prot. C13/RING 10 | 1.86 | 1.87 | Nuclear phosphoprotein | 3.5 | 2.81 |
| 256845 | 1.85 | 1.66 | LMP7 | 3.45 | 2.28 |
| Nuclear phosphoprotein | 1.8 | 1.49 | HLA II Ag DP1 | 3.39 | 2.44 |
| BAK1 | 1.76 | 1.72 | IDO | 3.19 | 2.59 |
| NMBD | 1.69 | 1.41 | 364744 | 3.12 | 2.89 |
| IFP-35 | 1.57 | 1.08 | Transthyretin | 3.06 | 2.5 |
| RING4 | 1.49 | 1.76 | BAK1 | 3 | 2.38 |
| ICAM-1 | 1.49 | 1.39 | ICAM-1 | 2.47 | 2.61 |
| IDO | 1.42 | 1.31 | 256845 | 2.35 | 2.15 |
| β-tubulin | 1.42 | 1.08 | Auto Ag SS-A/Ro | 2.33 | 1.96 |
| LMP2 | 1.4 | 1.49 | 214342 | 2.27 | 2.11 |
| 152074 | 1.34 | 1.15 | MHC I HLA-A3 | 2.18 | 1.71 |
| IL-15Rαc | 1.31 | 1.06 | DR-α | 2.16 | 1.42 |
| MHC I Ag B27 | 1.3 | 1.3 | Stannin | 2.15 | 1.84 |
| CG-12 | 1.26 | 1.04 | IRF-2 | 2.06 | 1.58 |
| HLA II Ag DP1 | 1.22 | 1.06 | IFP-35 | 2.03 | 1.84 |
| LMP7 | 1.19 | 1.32 | 9-27 | 2.01 | 1.97 |
aIncluding image ID number for unknown expressed sequence tags.
bFor HLA-E and IFP-53, two image clones corresponding to different regions of the mRNAs were represented on the arrays.
cFor IL-15R, two different image clones were present on the arrays. The basis for the minimal induction observed with one of the clones (1.31 at 6 h and <2 at 18 h) is not known.