Table 3.
Cox proportional hazard ratios for all cause mortality in patients with VTE.
| Categories | Model 1 | Model 2 | Model 3 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| HR (95 CI) | P value | P for trend | HR (95 CI) | P value | P for trend | HR (95 CI) | P value | P for trend | |
| 30-day mortality | |||||||||
| LAR (Continuous) | 1.41 (1.33–1.50) | <0.001 | 1.29 (1.19–1.40) | <0.001 | 1.18 (1.08–1.28) | <0.001 | |||
| LAR (Quartile) | <0.001 | <0.001 | <0.001 | ||||||
| Q1 (LAR <0.42) | |||||||||
| Q2 (0.42 ≤ LAR < 0.64) | 1.62 (1.14–2.29) | 0.007 | 1.47 (1.03–2.09) | 0.034 | 1.47 (1.03–2.09) | 0.033 | |||
| Q3 (0.64 ≤ LAR < 1.09) | 2.06 (1.47–2.87) | <0.001 | 1.67 (1.19–2.36) | 0.003 | 1.56 (1.11–2.21) | 0.011 | |||
| Q4 (LAR ≥ 1.09) | 3.54 (2.57–4.85) | <0.001 | 2.59 (1.84–3.65) | <0.001 | 2.02 (1.42–2.88) | <0.001 | |||
| 365-day mortality | |||||||||
| LAR (Continuous) | 1.41 (1.33–1.49) | <0.001 | 1.30 (1.20–1.39) | <0.001 | 1.18 (1.08–1.27) | <0.001 | |||
| LAR (Quartile) | <0.001 | <0.001 | <0.001 | ||||||
| Q1 (LAR <0.42) | |||||||||
| Q2 (0.42 ≤ LAR < 0.64) | 1.47 (1.07–2.12) | 0.017 | 1.34 (0.98–1.85) | 0.072 | 1.36 (0.99–1.87) | 0.061 | |||
| Q3 (0.64 ≤ LAR < 1.09) | 1.90 (1.40–2.56) | <0.001 | 1.56 (1.49–2.13) | 0.005 | 1.45 (1.06–1.98) | 0.02 | |||
| Q4 (LAR ≥ 1.09) | 3.20 (2.41–4.24) | <0.001 | 2.36 (1.73–3.22) | <0.001 | 1.83 (1.33–2.52) | <0.001 | |||
Model 1: adjusted for none.
Model 2: adjusted for age, weight, gender, race, heart rate, SpO2, respiratory rate, hematocrit, hemoglobin, RBC, WBC, bilirubin, creatinine, BUN, PCO2, PH, INR, PT, PTT.
Model 3: adjusted for age, weight, gender, race, heart rate, SpO2, respiratory rate, hematocrit, hemoglobin, RBC, WBC, bilirubin, creatinine, BUN, PCO2, PH, INR, PT, PTT, SOFA, APS III, AKI, hyperlipidemia, heart failure, coronary heart disease, hypertension, malignant cancer, ventilation, CRRT.
SpO2, oxygen saturation; RBC, red blood cell; WBC, white blood cell; BUN, blood urea nitrogen; PCO2, partial pressure of carbon dioxide; PH, potential of hydrogen; INR, international normalized ratio; PT, prothrombin time; PTT, partial thromboplastin time; SOFA, sequential organ failure assessment; APS III, acute physiology score III; AKI, ccute kidney injury; CRRT, continuous renal replacement therapy.