Table 4.
Prognostic accuracy of markers for 30-day and 365-day mortality.
| Prognostic marker | Cut-off | Sensitivity | Specificity | AUC (95%CI) | NPV | PPV |
|---|---|---|---|---|---|---|
| 30-day mortality | ||||||
| LAR | 0.894 | 0.485 | 0.727 | 0.649 (0.619–0.679) | 0.828 | 0.343 |
| Lactate | 2.550 | 0.451 | 0.745 | 0.636 (0.605–0.667) | 0.822 | 0.342 |
| Albumin | 2.750 | 0.549 | 0.577 | 0.565 (0.533–0.596) | 0.813 | 0.276 |
| SOFA | 5.5 | 0.653 | 0.535 | 0.635 (0.604–0.666) | 0.840 | 0.292 |
| LAR + SOFA | 0.209 | 0.508 | 0.755 | 0.670 (0.640–0.701) | 0.863 | 0.336 |
| 365-day mortality | ||||||
| LAR | 0.884 | 0.717 | 0.503 | 0.644 (0.614–0.673) | 0.856 | 0.302 |
| Lactate | 2.550 | 0.462 | 0.740 | 0.629 (0.599–0.658) | 0.850 | 0.301 |
| Albumin | 2.750 | 0.536 | 0.570 | 0.578 (0.548–0.608) | 0.834 | 0.232 |
| SOFA | 5.5 | 0.672 | 0.533 | 0.628 (0.599–0.657) | 0.869 | 0.259 |
| LAR + SOFA | 0.245 | 0.489 | 0.767 | 0.664 (0.636–0.693) | 0.836 | 0.380 |
LAR, lactate to albumin ratio; SOFA, sequential organ failure assessment; NPV, negative predictive value; PPV, positive predictive value.