1. Cytotoxic Activity (IC50, μM) of Studied Compounds Estimated by the MTT Assay .
a
Data are expressed as mean SD.
b
IC50 (μM)the half-maximal growth inhibitory concentration after cultured the cells for 72 h with the individual compound.
c
The SI (Selectivity Index) was calculated using formula: SI = IC50 for normal cell line/IC50 cancer cell line.
d
Human primary colon cancer (SW480).
e
Human metastatic colon cancer (SW620).
f
Human metastatic prostate cancer (PC3).
g
Human breast adenocarcinoma (MDA-MB-231).
h
Human immortal keratinocyte cell line from adult human skin (HaCaT).
i,j
The reference compounds.