Table 1.
Demographic variables
| Demographic variables | Diagnostic n = 33 |
Predictive n = 24 |
Overall n = 57 |
|||
|---|---|---|---|---|---|---|
| n | % | n | % | n | % | |
| Female | 25 | 76 | 20 | 83 | 45 | 79 |
| Male | 8 | 24 | 4 | 17 | 12 | 21 |
| Ethnicity | ||||||
| Asian (Indian/Pakistani) | 3 | 9 | 4 | 17 | 7 | 12 |
| White | 20 | 61 | 17 | 71 | 37 | 65 |
| Other | — | — | 1 | 4 | 1 | 2 |
| Undisclosed | 10 | 30 | 2 | 8 | 12 | 21 |
| Median | IQR | Median | IQR | Median | IQR | |
| Age, years | ||||||
| At LFS diagnosis | 40 | 32-52 | 36 | 28-41 | 38 | 29-48 |
| At 1st cancer diagnosis | 32 | 18-44 | 45 | 31-53 | 33 | 24-47 |
| F/u years from LFS diagnosis | 3 | 1-8 | 10 | 6-15 | 6 | 2-11 |
| Age at death, years (n = 25) | 44 | 38-60 | 44 | 37-49 | 44 | 38-58 |
| Age at loss to f/u, years (n = 33) median (IQR) | 41 | (30-54) | 46 | (43-56) | 46 | (41-54) |
| N | N | N | ||||
| Number of new primary cancer diagnoses | 78 | 14 | 92 | |||
| Recurrence (cancers) | 14 | 2 | 16 | |||
| Number of deaths | 21 | 4 | 25 | |||
| Number at last f/u | 13 | 20 | 33 | |||
| Treatments | N | % | N | % | N | % |
| Total | 129 | — | 25 | — | 154 | — |
| Radiotherapy curative | 16 | 12 | 3 | 12 | 19 | 12 |
| Radiotherapy palliative | 10 | 7 | 3 | 12 | 13 | 8 |
| Systemic anticancer treatment | 34 | 26 | 5 | 20 | 39 | 25 |
| Surgery | 61 | 47 | 11 | 44 | 72 | 47 |
| Other | 8 | 6 | 3 | 12 | 11 | 7 |
f/u, follow-up; IQR, interquartile range; LFS, Li Fraumeni syndrome.