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. 2025 Jun 25;6(10):101008. doi: 10.1016/j.xinn.2025.101008

Figure 2.

Figure 2

Cell growth and mutation burden

(A) Cell growth during passaging. Error bars present SD.

(B) Fractions of apoptotic cells. The p values were estimated using Student’s t test, one-tailed. Individual data points of the two passages are presented in Figure S2.

(C and D) (C) SNV burden and (D) INDEL burden per cell on log scales. Each data point represents a cell. The p values were estimated using linear mixed-effects models, two-tailed, using the “nlme” package of R.

Boxplot elements are defined as follows: center line indicates median, box limits indicate upper and lower quartiles, and whiskers indicate 1.5× interquartile range.