TABLE 3.
QoL, Emotional Well-Being, and Decision Regret
| Outcome Measures/Follow-up | Intervention Group, 95% CI | Control Group, 95% CI | P |
|---|---|---|---|
| Overall QoL | |||
| 8 weeks (n = 81/79) | 53.20 (50.78 to 55.63) | 53.64 (51.33 to 55.95) | .79 |
| 12 weeks (n = 82/78) | 54.04 (51.84 to 56.25) | 53.04 (50.24 to 55.85) | .58 |
| 24 weeks (n = 80/68) | 51.81 (49.56 to 54.07) | 51.41 (48.32 to 54.51) | .83 |
| Emotional functioning | |||
| 8 weeks (n = 81/79) | 48.91 (47.01 to 50.80) | 49.59 (47.83 to 51.36) | .59 |
| 12 weeks (n = 82/78) | 51.07 (49.12 to 53.03) | 49.36 (47.24 to 51.47) | .24 |
| 24 weeks (n = 80/68) | 50.21 (48.14 to 52.28) | 49.52 (47.14 to 51.91) | .66 |
| Physical functioning | |||
| 8 weeks (n = 81/79) | 47.05 (45.14 to 48.93) | 47.67 (45.84 to 49.48) | .64 |
| 12 weeks (n = 82/78) | 47.46 (45.45 to 49.46) | 46.04 (43.74 to 48.34) | .36 |
| 24 weeks (n = 80/68) | 48.05 (46.21 to 59.89) | 46.27 (43.91 to 48.63) | .50 |
| Nausea/vomitinga | |||
| 8 weeks (n = 81/79) | 51.74 (51.74-53.90) | 51.74 (51.74-51.74) | .53b |
| 12 weeks (n = 82/78) | 51.74 (51.74-51.74) | 51.74 (51.74-51.74) | .58b |
| 24 weeks (n = 80/68) | 51.74 (51.74-51.74) | 51.74 (51.74-56.96) | .55b |
| Fatigue | |||
| 8 weeks (n = 81/79) | 56.15 (54.56 to 57.75) | 55.79 (54.11 to 57.48) | .76 |
| 12 weeks (n = 82/78) | 55.49 (53.63 to 57.34) | 55.38 (53.35 to 57.40) | .94 |
| 24 weeks (n = 80/68) | 55.12 (53.05 to 57.19) | 54.22 (51.87 to 56.57) | .56 |
| Anxiety | |||
| 8 weeks (n = 80/66) | 4.92 (4.03 to 5.82) | 4.80 (3.96 to 5.64) | .81 |
| 12 weeks (n = 79/69) | 4.72 (3.80 to 5.64) | 4.58 (3.60 to 5.56) | .83 |
| 24 weeks (n = 75/62) | 5.09 (4.11 to 6.08) | 4.89 (3.86 to 5.91) | .77 |
| Depression | |||
| 8 weeks (n = 80/67) | 3.08 (2.38 to 3.77) | 2.73 (2.13 to 3.33) | .46 |
| 12 weeks (n = 79/69) | 3.48 (2.68 to 4.28) | 2.88 (2.21 to 3.56) | .26 |
| 24 weeks (n = 75/61) | 3.30 (2.55 to 4.04) | 2.49 (1.84 to 3.14) | .12 |
| Total anxiety and depression | |||
| 8 weeks (n = 80/66) | 8.00 (6.53 to 9.47) | 7.58 (6.31 to 8.85) | .67 |
| 12 weeks (n = 79/69) | 8.20 (6.64 to 9.77) | 7.5 (5.94 to 9.06) | .53 |
| 24 weeks (n = 75/61) | 8.39 (6.77 to 10.00) | 7.29 (5.74 to 8.85) | .34 |
| Decision regreta | |||
| Baseline (n = 98/96) | 0 (0-15) | 0 (0-20) | .47b |
| 8 weeks (n = 80/65) | 5 (0-20) | 5 (0-20) | .99b |
Abbreviation: QoL, quality of life.
a
Median and percentiles (25th percentile-75th percentile).
b
Wilcoxon rank-sum test.