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. 2025 Oct 3;12:1672939. doi: 10.3389/fmed.2025.1672939

Table 2.

Case data of 27 acute leukemia patients with rhinocerebral mucormycosis.

Case reports Age and sex Type of disease Surgical debridement Therapeutic drugs Effective remission of the infection
Ding et al. (16) 46/F AML Yes AmB No
Yamamoto et al. (17) 42/M AML Yes L-AmB, micafungin Yes
Popa et al. (18) 7/F ALL Yes AmB Yes
Yang et al. (19) 1/M ALL No AmB, posaconazole No
Yeung et al. (20) 57/M AML M5a No L-AmB, imipenem, amikacin No
Samanta et al. (21) 8/M ALL Yes L-AmB Yes
Siriwardena et al. (22) 35/F AML Yes L-AmB No
Siriwardena et al. (22) 29/F AML Yes L-AmB, antibiotics Yes
Siriwardena et al. (22) 42/M AML Yes L-AmB No
Hu et al. (23) 1/M ALL No L-AmB, voriconazole No
Ojeda-Diezbarroso et al. (24) 12/F ALL Yes L-AmB, posaconazole Yes
Uraguchi et al. (25) 70/M AML M5b Yes L-AmB, antibiotics No
Wehl et al. (26) 1/M ALL No L-AmB, antibiotics No
Mutchnick et al. (27) 2/M ALL Yes AmB, posaconazole, micafungin Yes
Dworsky et al. (28) 17/F BCP-ALL Yes L-AmB, micafungin Yes
Gumral et al. (29) 40/M ALL Yes L-AmB Yes
Raj et al. (30) 55/M APL Yes L-AmB Yes
Sigera et al. (31) 19/M B-ALL Yes L-AmB No
Lerchenmüller et al. (32) 28/M ALL Yes L-AmB Yes
Cofré et al. (33) 2/F ALL Yes AmB Yes
Ammon et al. (34) 24/F AML No AmB, flucytosine Yes
Jacobs et al. (35) 35/F AML No AmB No
Jacobs et al. (35) 17/M ALL No AmB, echinocandin FK463 Yes
Parkyn et al. (36) 3/M BCP-ALL No L-AmB Yes
Andreani et al. (37) 59/M sAML Yes L-AmB, isavuconazole Yes
Funada et al. (38) 21/M BCP-ALL No AmB Yes
Brusis and Rister (39) 12/M ALL Yes AmB Yes

F, female; AML, acute myeloid leukemia; AmB, amphotericin B; M, male; L-AmB, liposomal amphotericin B; ALL, acute lymphoblastic leukemia; AML M5a, acute monoblastic leukemia; AML M5b, acute monocytic leukemia; BCP-ALL, B-cell precursor acute lymphoblastic leukemia; APL, acute promyelocytic leukemia; B-ALL, B-cell acute lymphoblastic leukemia; sAML, secondary acute myeloid leukemia.