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. 2025 Oct 3;13:1677422. doi: 10.3389/fbioe.2025.1677422

TABLE 2.

ALP activity and expression of dental source marker genes under different induction media cultivation (Ruth et al., 2015).

Experimental group category Alkaline phosphatase (ALP) activity The mRNA expression of odontogenic marker genes (including DLX5, RUNX2, BGLAP, DMP1 and DSPP) at different time points
Non-induced CD51/CD140α DMSCs Control group /
Induced CD271 DMSCs Increased by five times compared with the control group On Day 10, concurrently with the notable induction of BGLAP expression, the expressions of DMP1 and DSPP were significantly upregulated during the induction process
Induced CD51/CD140α DMSCs Increased by 2.5 times compared with the control group On Day 7, the expression of DLX5 was significantly increased. On Day 10, the expressions of DMP1 and DSPP were significantly upregulated after induction
Induced STRO-1/CD146 DMSCs Increased by 1.25 times compared with the control group On Day 10, the expressions of DMP1 and DSPP were significantly upregulated