TABLE 2.
ALP activity and expression of dental source marker genes under different induction media cultivation (Ruth et al., 2015).
| Experimental group category | Alkaline phosphatase (ALP) activity | The mRNA expression of odontogenic marker genes (including DLX5, RUNX2, BGLAP, DMP1 and DSPP) at different time points |
|---|---|---|
| Non-induced CD51/CD140α DMSCs | Control group | / |
| Induced CD271 DMSCs | Increased by five times compared with the control group | On Day 10, concurrently with the notable induction of BGLAP expression, the expressions of DMP1 and DSPP were significantly upregulated during the induction process |
| Induced CD51/CD140α DMSCs | Increased by 2.5 times compared with the control group | On Day 7, the expression of DLX5 was significantly increased. On Day 10, the expressions of DMP1 and DSPP were significantly upregulated after induction |
| Induced STRO-1/CD146 DMSCs | Increased by 1.25 times compared with the control group | On Day 10, the expressions of DMP1 and DSPP were significantly upregulated |