TABLE 8.
Application of DFSCs in bone tissue repair.
| Cell type | Material/scaffold | Experimental model | Experimental subject | Results and conclusions | References |
|---|---|---|---|---|---|
| DFSCs | NAC | Alveolar bone defect | rat | It has the potential to enhance the osteogenic differentiation ability. It enriches genes associated with the “developmental process”, decreases the intracellular ROS levels, and strengthens the antioxidant capacity | Meng et al. (2022) |
| DFSCs | HOTAIRM1 | Skull defect | rat | Regulating the demethylation of H3K27 promotes osteogenic differentiation of DFSCs and shows stronger ALP activity and mineralized nodule formation ability under hypoxic conditions | Chen et al. (2023) |
DFSCs, Dental follicle stem cells; NAC, N-acetylcysteine; ROS, reactive oxygen species; ALP, alkaline phosphatase.