Table 3.
Procalcitonin levels, SOFA and APACHE II scores
| Measurement | Day 1 | Day 2 | Day 3 | Day 4 | Day 5 | Day 6 | Day 7 | Day 8 | ANOVA |
| PCT (ng/mL) | |||||||||
| Pentaglobin® | 5.5 (0.9–72.0) | 3.5* (0.9–65.0) | 3.5** (0.9–39.0) | 3.05* (0.9–23.0) | 2.6* (0.8–11.0) | 2.45 (0.6–11.0) | 2.0* (0.6–11.0) | 1.45** (0.6–14.3) | <0.001 |
| Control | 4.0 (0.4–194.0) | 3.14 (0.4–72.0) | 3.2 (0.2–34.0) | 2.65 (0.6–18.0) | 3.15 (0.5–14.0) | 4.0 (0.6–21.6) | 4.0 (0.3–117.0) | 4.0 (0.5–185.0) | 0.8 |
| SOFA | |||||||||
| Pentaglobin® | 5.0 (1.0–10.0) | 6.0 (1.0–11.0) | 6.0 (0–12) | 5.0 (0–16) | 4.0 (0.0–16.0) | 4.0 (0–16) | 3.5 (0.0–15.0) | 4.0 (0–14) | 0.2 |
| Control | 4.5 (1.0–12.0) | 5.5 (1.0–15.0) | 5.0 (2–15) | 5.0 (2–12) | 4.5 (1.0–10.0) | 5.0 (1–11) | 4.0 (1.0–11.0) | 6.0 (0–10) | 0.3 |
| APACHE II | |||||||||
| Pentaglobin® | 15.0 (9–24) | 14.0 (8.0–28.0) | 14.0 (7–24) | 13.0 (7–30) | 11.0 (5.0–30.0) | 11.5* (5.0–30.0) | 12.5 (5.0–30.0) | 8.0** (5–30) | < 0.001 |
| Control | 16.0 (3–27) | 15.5 (5.0–27.0) | 16.0 (5–24) | 15.0 (4–22) | 11.5** (3.0–21.0) | 11.0** (1.0–27.0) | 11.0** (1.0–21.0) | 11.0** (1–16) | < 0.001 |
Values are expressed as median (range). ANOVA, analysis of variance; APACHE II, acute physiological and chronic health evaluation; PCT, procalcitonin; SOFA, sequential organ failure assessment. *P < 0.05, **P < 0.01 when compared to Day 1.