Figure 6.
Tissue context of human trait associations
(A) Heatmap of enrichment (log2 odds ratio) for trait-associated probes across chromatin states; columns are studies, and rows are chromatin states.
(B) Distributions of tissue mean beta value ranks across trait-associated CpGs.
(C) Enrichment of MSA tissue-specific methylation sets in various traits’ GWAS SNPs (one-tailed Fisher’s test, color indicates −log10[FDR-adjusted p value]).
