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. 2025 Jul 3;5(9):100929. doi: 10.1016/j.xgen.2025.100929

Figure 6.

Figure 6

Tissue context of human trait associations

(A) Heatmap of enrichment (log2 odds ratio) for trait-associated probes across chromatin states; columns are studies, and rows are chromatin states.

(B) Distributions of tissue mean beta value ranks across trait-associated CpGs.

(C) Enrichment of MSA tissue-specific methylation sets in various traits’ GWAS SNPs (one-tailed Fisher’s test, color indicates −log10[FDR-adjusted p value]).