Table I. Genotypic distribution of embryos and mice from TACC3 heterozygous intercrosses.
Stage | No. of litters | Total No. | TACC3(+/+) | TACC3(+/–) | TACC3(–/–) | (–/–) % |
---|---|---|---|---|---|---|
9.5–10.5 | 7 | 68 | 24 | 28 | 16 | 23.5 |
10.5–11.5 | 6 | 45 | 8 | 28 | 9 | 20 |
12–12.5 | 10 | 74 | 25 | 41 | 8 | 10.8 |
13–13.5 | 24 | 165 | 53 | 93 | 19 | 11.5 |
14–15.5 | 42 | 302 | 104 | 170 | 28 | 9.3 |
16–17.5 | 31 | 189 | 53 | 113 | 23 | 12.2 |
18–19 | 31 | 215 | 73 | 130 | 12 | 5.6 |
Newborns | 55 | 297 | 88 | 209 | (4)a | (1.3) |
Embryos were collected between days 9.5 and 19.0 of pregnancy from TACC3(+/–) intercrosses. The frequency of mutant embryos is indicated in the table as a percentage of the total number of embryos analyzed. aNewborns found on day 1 were dead.