Table 1.
Demographic data of previously-reported cases of cocaine-induced renal infarction.
| Characteristics | Wohlman [11] | Antonovych [13] | Kramer [12] | Goodman [14] | Saleem [15] | Edmondson [16] | Mochizuki [17] |
| Age (s) | 32 | 39, 26 | 37 | 37 | 25 | 40 | 52 |
| Sex | Male | Males | Male | Male | Male | Male | Female |
| Route | IV | NR | NR | IN | IN | NR | IN |
| Time of Onset | 2 hours | NR | 2–3 hours | 2 hours | 4 days | 1 day | NR |
| Kidney Affected | Right | NR | Right | Right | Right | Right | Left |
| WBC (× 103/μl) | 14 | NR | 23 (8% bands) | 16 (90% PMN) | 12.3 (76% PMN) | NR | 19.3 |
| Serum LDH (U/L) | 368 to 1860 | NR | 2103 | NR | 351 | NR | 2100 |
| Serum Cr (mg/dL) | 1.2 | NR | 1.7 | 0.9 | NR | 1.3 | 0.9 |
| Urinanalysis | 5–10 RBC | NR | trace protein 3+ ketones 2+ blood 3–4 WBC/hpf 1–2 RBC/hpf |
30 protein 80 ketones 1–5 WBC/hpf 5–10 RBC/hpf |
2+ blood 2 WBC/hpf 5–10 RBC/hpf |
0 RBC/hpf | trace protein large blood 3 WBC/hpf 1 RBC/hpf |
| Treatment | heparin & coumadin | nephrectomy | urokinase, heparin & coumadin | none | aspirin | heparin & coumadin | heparin, antibiotics & coumadin |
| Co-existing Conditions | NR | NR | DM, Protein C deficiency | NR | NR | Renal artery dissection | Aortic thrombosis |
WBC (White Blood Cell; cells × 103/ul = cells × 109/ul); RBC (Red Blood Cell); hpf (High Power Field); LDH (Lactate Dehydrogenase); PMN (Polymorphonuclear Cells); N/R (Not Reported); IV (Intravenous); IN (Intra-nasal); DM (Diabetes Mellitus); Serum Cr (Serum Creatinine; 1 mg/dL = 88.4 umol/L)