Table 4.
Results of regression of SCD-specific variables on SF-36 subscales, controlling for socio-demographic variables1 (regression coefficients ± standard error)
| Genotype2 | Mean pain | Proportion Days with Crisis3 | Proportion Days with Utilization4 | |
| Physical Function | -5.01 ± 3.30 | -4.55 ± 0.72** | -0.42 ± 2.12 | 3.51 ± 1.97 |
| Role-Physical | -1.62 ± 5.73 | -6.12 ± 1.27** | -0.91 ± 3.70 | 2.75 ± 3.39 |
| Bodily Pain | 0.14 ± 3.57 | -4.41 ± 0.79** | -5.93 ± 2.31* | -0.59 ± 2.13 |
| General Health | 3.52 ± 3.19 | -3.34 ± 0.71** | -1.31 ± 2.09 | -1.44 ± 1.92 |
| Vitality | 6.43 ± 3.27* | -3.54 ± 0.72** | 0.55 ± 2.10 | 3.06 ± 1.94 |
| Social Function | 3.16 ± 3.77 | -4.27 ± 0.82** | -3.28 ± 2.44 | 1.93 ± 2.25 |
| Role-emotional | 7.06 ± 6.27 | -5.81 ± 1.39** | 2.30 ± 4.09 | 2.12 ± 3.71 |
| Mental Health | 4.23 ± 3.14 | -1.44 ± 0.69* | -1.53 ± 2.02 | 0.35 ± 1.87 |
1controlling for age, gender, years of education
2SS and Sßo Thalasemia vs SC and Sß+ Thalasemia
3Percent of days with crises: 0, 0.1–10,10+ (coded 1,2,3)
4Percent of days with utilization: 0, 0.1–3, 3+ (coded 1,2,3)
*p ≤ 0.05; **p < 0.0001