Table 2.

The effect of demographic characteristics on clinically relevant variation in function over two years

	KOOS Activities of Daily Living					SF-36 Physical Function
Characteristic	Prevalence of clinically relevant change		Unadjusted for baseline values	Adjusted for baseline values		Prevalence of clinically relevant change		Unadjusted for baseline values	Adjusted for baseline value
	N	%	OR	OR	95% CI	N	%	OR	OR	95% CI
Age
<46†	6/49	12				21/49	43
46–56	19/47	40	4.5	3.8	1.2–12.4	24/45	53	1.2	0.9	0.3–2.4
>56	13/47	28	2.5	1.8	0.5–6.2	23/46	50	1.3	0.5	0.2–1.4
Gender
men†	32/120	27				54/118	46
women	6/23	26	1.2	0.7	0.2–2.3	14/22	64	2.4	1.9	0.6–6.1
BMI (kg/m2)
<25†	9/61	15				21/60	35
25–29.9	22/64	34	1.4	2.0	0.5–3.9	39/63	62	3.2	2.4	1.0–5.7
≥30	7/16	44	1.4	1.8	0.3–6.3	6/15	40	1.2	0.1	0.2–0.9

KOOS = Knee injury and Osteoarthritis Outcome Score, OR = odds ratio, 95% CI = 95% confidence interval, BMI = body mass index.

* All risk factors listed are entered simultaneously in each model.

† Reference category.