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. 2005 Oct 4;102(41):14907–14912. doi: 10.1073/pnas.0507440102

Fig. 2.

Fig. 2.

E2 treatment (24 h) increases the amplitude of spontaneous synaptic activity in both ♂ and ♀ VMN neurons. (A and B) Histograms illustrate the overall spontaneous synaptic activity amplitude before and after E2 treatment (10 nM) in ♂ and ♀ neurons: all events (A1 and B1), largest 10% events (A2 and B2), and lowest 10% events (A3 and B3). (A1 and B1) Of all events, spontaneous synaptic activity amplitude was increased in both ♂ (median of control, 55.94 pA; E2 treated, 59.20 pA; P < 0.0001) and ♀ neurons (median of control, 56.76 pA; E2 treated, 65.92 pA; P < 0.0001). Of the largest 10% events, the amplitude showed more significant increase by E2 treatment in ♂ (A2, control, 264 pA; E2 treated, 526 pA; P < 0.0001) and ♀ neurons (B2, control, 358 pA; E2 treated, 828 pA; P < 0.0001). Of the lowest 10% events, the amplitude showed less significant difference in ♂ (A3, control, 31.74 pA; E2 treated, 32.35 pA; P < 0.05) and ♀ neurons (B3, control, 31.72 pA; E2 treated, 32.43 pA; P < 0.0001).