Fig. 5.
Acute (5-min) E2 treatment alone changed mIPSCs in ♂ and ♀ neurons. (A) Recording traces (A1) and histograms (A2 and A3) show that acute E2 treatment significantly increased the event interval and hence decreased the frequency (A2; P < 0.01) but increased the amplitude (A3; P < 0.01) in ♂ neurons. (B) Recording traces (B1) and histograms (B2 and B3) show that acute E2 treatment significantly decreased mIPSCs frequency (B2; P < 0.0001) but increased the amplitude (B3; P < 0.0001) in ♀ neurons.