Table 2.
Rate of isolates resulting in synergistic interaction according to checkerboard combination tests (number of isolates resulting in synergistic interaction/total number of isolates).
| Inhibitory substances | Aspergillus species (n=4) | Rhizopus oryzae (n=3) | Fusarium oxysporum (n=3) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ITRA | VOR | CAS | AMB | ITRA | VOR | CAS | AMB | ITRA | VOR | CAS | AMB | |
| RAP | 0.75 | 0.25 | 0 | 0.50 | 1.00 | 0.33 | 0 | 0.66 | 0.66 | 0.33 | 0 | 0 |
| TAC | 0 | 0 | 0 | 0.25 | 0 | 0 | 1.00 | 0.33 | 0 | 0.33 | 0.33 | 0 |
| CICA | 0.75 | 0.25 | 0 | 0.25 | 0.66 | 0 | 0 | 1.00 | 0 | 0.33 | 0.33 | 0.33 |
| GELD | 1.00 | 0.50 | 0 | 1.00 | 0.66 | 0.33 | 0 | 0.66 | 0 | 0.33 | 0.33 | 0.33 |
| RDC | 0.75 | 0.25 | 0 | 0.5 | 1.00 | 0 | 0 | 0.33 | 0 | 0 | 0.33 | 0 |
| NOV | 0.75 | 0.50 | 0 | 0.75 | 0.33 | 0 | 0 | 0.33 | 0.33 | 0.33 | 0.33 | 0 |
| 17-AAG | 1.00 | 0.50 | 0.25 | 0.25 | 0.66 | 0 | 0 | 0.66 | 0 | 0.33 | 0 | 0.66 |
ITRA: itraconazole; VOR: voriconazole; CAS: caspofungin; AMB: amphotericin B; RAP: rapamycin; TAC: tacrolimus; CICA: cyclosporin A; GEL: geldanamycin; RDC: radicicol; NOV: novobiocin; 17-AAG: 17-allylamino-17-demethoxygeldanamycin.