Table 2.
RRs for selected cancers, by lifetime exposure-days to carbofuran among AHS (1993–1997) applicators with nonexposed and low-exposed groups as referents.
Lifetime exposure daysa | Cases (n) | Nonexposed referent RR (95% CI) | Low-exposed referent RR (95% CI) |
---|---|---|---|
All cancers | |||
0 | 1,012 | 1.0 | |
> 0–9 | 151 | 0.95 (0.80–1.14) | 1.0 |
10–39 | 115 | 0.95 (0.78–1.15) | 1.00 (0.78–1.27) |
40–109 | 80 | 1.05 (0.83–1.33) | 1.11 (0.83–1.49) |
> 109 | 51 | 0.94 (0.70–1.26) | 0.96 (0.67–1.37) |
Trendb | 0.79 | 0.94 | |
Lymphatic–hematopoietic cancers | |||
0 | 103 | 1.0 | |
> 0–9 | 11 | 0.68 (0.36–1.30) | 1.0 |
10–39 | 10 | 0.82 (0.42–1.60) | 1.05 (0.44–2.51) |
40–109 | 11 | 1.38 (0.72–2.65) | 1.56 (0.62–3.92) |
> 109 | 5 | 0.86 (0.34–2.23) | 0.77 (0.23–2.57) |
Trendb | 0.93 | 0.74 | |
Non-Hodgkin lymphoma | |||
0 | 44 | 1.0 | |
> 0–9 | 6 | 0.77 (0.31–1.86) | 1.0 |
10–39 | 7 | 1.27 (0.55–2.91) | 1.33 (0.44–4.02) |
40–109 | 7 | 1.40 (0.59–3.30) | 1.08 (0.31–3.74) |
Trendb | 0.40 | 0.94 | |
Colon | |||
0 | 80 | 1.0 | |
> 0–9 | 10 | 0.88 (0.45–1.72) | 1.0 |
10–39 | 9 | 0.99 (0.49–2.02) | 1.03 (0.41–2.56) |
40–109 | 5 | 0.84 (0.33–2.12) | 0.77 (0.25–2.42) |
> 109 | 6 | 1.34 (0.54–3.31) | 1.16 (0.36–3.71) |
Trendb | 0.68 | 0.85 | |
Lung | |||
0 | 98 | 1.0 | |
> 0–9 | 6 | 0.42 (0.18–0.97) | 1.0 |
10–39 | 8 | 0.68 (0.33–1.43) | 1.61 (0.55–4.69) |
40–109 | 9 | 1.09 (0.54–2.22) | 2.54 (0.85–7.67) |
> 109 | 8 | 1.38 (0.63–2.99) | 3.05 (0.94–9.87) |
Trendb | 0.46 | 0.07 | |
Prostate | |||
0 | 372 | 1.0 | |
> 0–9 | 85 | 1.30 (1.01–1.66) | 1.0 |
10–39 | 48 | 0.99 (0.73–1.35) | 0.79 (0.55–1.13) |
40–109 | 29 | 1.03 (0.70–1.53) | 0.86 (0.55–1.36) |
> 109 | 17 | 0.88 (0.53–1.47) | 0.73 (0.41–1.31) |
Trendb | 0.70 | 0.34 |
Rate ratios adjusted for age, sex, education, family history of cancer, smoking, alcohol, year of enrollment, state of residence, and exposure to EPTC, fonofos, trichlorofon, chlorpyrifos, and permethrin.
Years of use × days of use per year.
p-Value for trend test.