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. 2004 Dec 2;113(3):285–289. doi: 10.1289/ehp.7451

Table 2.

RRs for selected cancers, by lifetime exposure-days to carbofuran among AHS (1993–1997) applicators with nonexposed and low-exposed groups as referents.

Lifetime exposure daysa Cases (n) Nonexposed referent RR (95% CI) Low-exposed referent RR (95% CI)
All cancers
 0 1,012 1.0
 > 0–9 151 0.95 (0.80–1.14) 1.0
 10–39 115 0.95 (0.78–1.15) 1.00 (0.78–1.27)
 40–109 80 1.05 (0.83–1.33) 1.11 (0.83–1.49)
 > 109 51 0.94 (0.70–1.26) 0.96 (0.67–1.37)
 Trendb 0.79 0.94
Lymphatic–hematopoietic cancers
 0 103 1.0
 > 0–9 11 0.68 (0.36–1.30) 1.0
 10–39 10 0.82 (0.42–1.60) 1.05 (0.44–2.51)
 40–109 11 1.38 (0.72–2.65) 1.56 (0.62–3.92)
 > 109 5 0.86 (0.34–2.23) 0.77 (0.23–2.57)
 Trendb 0.93 0.74
Non-Hodgkin lymphoma
 0 44 1.0
 > 0–9 6 0.77 (0.31–1.86) 1.0
 10–39 7 1.27 (0.55–2.91) 1.33 (0.44–4.02)
 40–109 7 1.40 (0.59–3.30) 1.08 (0.31–3.74)
 Trendb 0.40 0.94
Colon
 0 80 1.0
 > 0–9 10 0.88 (0.45–1.72) 1.0
 10–39 9 0.99 (0.49–2.02) 1.03 (0.41–2.56)
 40–109 5 0.84 (0.33–2.12) 0.77 (0.25–2.42)
 > 109 6 1.34 (0.54–3.31) 1.16 (0.36–3.71)
 Trendb 0.68 0.85
Lung
 0 98 1.0
 > 0–9 6 0.42 (0.18–0.97) 1.0
 10–39 8 0.68 (0.33–1.43) 1.61 (0.55–4.69)
 40–109 9 1.09 (0.54–2.22) 2.54 (0.85–7.67)
 > 109 8 1.38 (0.63–2.99) 3.05 (0.94–9.87)
 Trendb 0.46 0.07
Prostate
 0 372 1.0
 > 0–9 85 1.30 (1.01–1.66) 1.0
 10–39 48 0.99 (0.73–1.35) 0.79 (0.55–1.13)
 40–109 29 1.03 (0.70–1.53) 0.86 (0.55–1.36)
 > 109 17 0.88 (0.53–1.47) 0.73 (0.41–1.31)
 Trendb 0.70 0.34

Rate ratios adjusted for age, sex, education, family history of cancer, smoking, alcohol, year of enrollment, state of residence, and exposure to EPTC, fonofos, trichlorofon, chlorpyrifos, and permethrin.

a

Years of use × days of use per year.

b

p-Value for trend test.