Table 3.

RRs for lung cancer by carbofuran intensity-weighted lifetime exposure days, exposure frequency (days per year), and exposure duration (years of use) in the AHS (1993–1997).

	Cases (n)	Full model RR (95% CI)a	Reduced model RR (95% CI)b
Intensity-weighted lifetime exposure daysc
> 0–63	6	1.0	1.0
64–196	11	2.11 (0.77–5.78)	2.42 (0.89–6.54)
197–487	5	1.19 (0.35–4.03)	1.58 (0.48–5.19)
> 487	9	2.10 (0.69–6.39)	3.40 (1.21–9.58)
Trendd		0.40	0.23
Days of use/year
< 5	9	1.0	1.0
5–9	9	1.53 (0.59–3.95)	1.67 (0.66–4.21)
10–19	9	2.98 (1.07–8.33)	3.84 (1.52–9.71)
≥ 20	4	4.13 (1.13–15.08)	5.63 (1.73–18.35)
Trendd		< 0.01	< 0.01
Years of use
≤ 5	16	1.0	1.0
6–10	6	0.80 (0.30–2.10)	1.00 (0.39–2.55)
> 10	9	1.95 (0.80–4.77)	3.00 (1.32–6.81)
Trendd		0.02	< 0.01

^aRate ratios adjusted for age, sex, education, family history of cancer, smoking, alcohol, year of enrollment, state of residence, and exposure to EPTC, fonofos, trichlorofon, chlorpyrifos, and permethrin.

^bRate ratios adjusted for age, smoking (never, < 14 pack-years, ≥ 14 pack-years), family history of cancer, and exposure to trichlorofon and permethrin.

^cYears of use × days of use per year × intensity score.

^dp-Value for trend test.