Table 2.
Intrachild tolerance interval for
|
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---|---|---|---|---|---|---|---|---|---|
Interchild tolerance interval for populationb |
Individual with mean of Lpc |
Individual with mean of μd |
Individual with mean of Upe |
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Compound | Overall population geometric meana (μ) | LP | UP | LIL | UIL | Lμ | Uμ | LIU | UIU |
Benzene | 0.063 | 0.026 | 0.152 | 0.007 | 0.097 | 0.017 | 0.233 | 0.042 | 0.559 |
Carbon tetrachloride | 0.005 | 0.002 | 0.011 | 0.001 | 0.006 | 0.002 | 0.014 | 0.004 | 0.030 |
1,4-Dichlorobenzene | 0.242 | 0.001 | 56.436 | 0.000 | 0.012 | 0.021 | 2.728 | 5.009 | 635.803 |
Ethylbenzene | 0.033 | 0.012 | 0.087 | 0.004 | 0.035 | 0.012 | 0.092 | 0.031 | 0.244 |
Styrene | 0.110 | 0.027 | 0.450 | 0.005 | 0.149 | 0.020 | 0.608 | 0.082 | 2.487 |
Tetrachloroethylene | 0.033 | 0.006 | 0.173 | 0.002 | 0.024 | 0.009 | 0.127 | 0.045 | 0.661 |
Toluene | 0.117 | 0.045 | 0.306 | 0.017 | 0.121 | 0.043 | 0.315 | 0.114 | 0.824 |
Trichloroethene | 0.007 | 0.005 | 0.011 | 0.003 | 0.008 | 0.004 | 0.012 | 0.007 | 0.018 |
1,1,1-Trichloroethane | 0.027 | 0.018 | 0.041 | 0.012 | 0.029 | 0.017 | 0.043 | 0.026 | 0.064 |
m-/p-Xylene | 0.172 | 0.074 | 0.401 | 0.024 | 0.230 | 0.055 | 0.536 | 0.129 | 1.249 |
o-Xylene | 0.039 | 0.015 | 0.100 | 0.006 | 0.041 | 0.014 | 0.105 | 0.037 | 0.271 |
μ = 10mean[log(x)], the estimated geometric mean, calculated by back-transforming the average of within-child mean log concentrations.
(LP, UP) = 95% tolerance interval for the population of individual mean serum levels, calculated using between-child SD, σP, for the log-transformed data and back-transforming: log(μ) ± 1.96σP.
(L IL, U IL) = Tolerance interval for an individual with mean serum level equal to the lower tolerance limit of the population, LP, and calculated using within-child SD, σI, and back-transforming: log(LP) ± 1.96σI.
(L μ, U μ) = Tolerance interval for an individual with mean serum level equal to the estimated geometric mean of the population, μ, and calculated using within-child SD, σI, and back-transforming: log(μ) ± 1.96σI.
(L IU, U IU) = Tolerance interval for an individual with mean level equal to the upper tolerance limit of the population, UP, calculated using within-child SD, σI, and back-transforming: log(UP) ± 1.96σI.