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. 2004 Nov 22;113(3):342–349. doi: 10.1289/ehp.7412

Table 2.

Summary of intrachild and interchild variability for blood VOC concentrations (ng/mL).

Intrachild tolerance interval for
Interchild tolerance interval for populationb
Individual with mean of Lpc
Individual with mean of μd
Individual with mean of Upe
Compound Overall population geometric meana (μ) LP UP LIL UIL Lμ Uμ LIU UIU
Benzene 0.063 0.026 0.152 0.007 0.097 0.017 0.233 0.042 0.559
Carbon tetrachloride 0.005 0.002 0.011 0.001 0.006 0.002 0.014 0.004 0.030
1,4-Dichlorobenzene 0.242 0.001 56.436 0.000 0.012 0.021 2.728 5.009 635.803
Ethylbenzene 0.033 0.012 0.087 0.004 0.035 0.012 0.092 0.031 0.244
Styrene 0.110 0.027 0.450 0.005 0.149 0.020 0.608 0.082 2.487
Tetrachloroethylene 0.033 0.006 0.173 0.002 0.024 0.009 0.127 0.045 0.661
Toluene 0.117 0.045 0.306 0.017 0.121 0.043 0.315 0.114 0.824
Trichloroethene 0.007 0.005 0.011 0.003 0.008 0.004 0.012 0.007 0.018
1,1,1-Trichloroethane 0.027 0.018 0.041 0.012 0.029 0.017 0.043 0.026 0.064
m-/p-Xylene 0.172 0.074 0.401 0.024 0.230 0.055 0.536 0.129 1.249
o-Xylene 0.039 0.015 0.100 0.006 0.041 0.014 0.105 0.037 0.271
a

μ = 10mean[log(x)], the estimated geometric mean, calculated by back-transforming the average of within-child mean log concentrations.

b

(LP, UP) = 95% tolerance interval for the population of individual mean serum levels, calculated using between-child SD, σP, for the log-transformed data and back-transforming: log(μ) ± 1.96σP.

c

(L IL, U IL) = Tolerance interval for an individual with mean serum level equal to the lower tolerance limit of the population, LP, and calculated using within-child SD, σI, and back-transforming: log(LP) ± 1.96σI.

d

(L μ, U μ) = Tolerance interval for an individual with mean serum level equal to the estimated geometric mean of the population, μ, and calculated using within-child SD, σI, and back-transforming: log(μ) ± 1.96σI.

e

(L IU, U IU) = Tolerance interval for an individual with mean level equal to the upper tolerance limit of the population, UP, calculated using within-child SD, σI, and back-transforming: log(UP) ± 1.96σI.