Fig. 2. (A) Alignment of Orf1 with the precursors of LS-BP and LIV-BP from E.coli. Residues interacting with the α-carboxyl and α-amino groups of the ligand (leucine) are marked by diamonds and residues forming the hydrophobic binding pocket are indicated by asterisks. (B) Alignment of Orf2 with OpuCC and OpuBC of B.subtilis. Putative signal peptides are indicated and the peptidase cleavage sites are marked by vertical arrows. Conserved and similar residues are boxed in black and grey, respectively.