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. 2025 Oct 14;2025:9058296. doi: 10.1155/ccrp/9058296

Table 2.

Laboratory variables and SOFA scores of the patients studied.

Variables Stroke group No-stroke group p value
At ECMO initiation
Hemoglobin (gm/L) 95 (84, 108) 100 (88, 112) 0.35
Platelet count (109/L) 103 (53, 157) 97 (59, 182) 0.71
Serum creatinine (μmol/L) 113 (86, 138) 105 (66, 152) 0.48
Serum bilirubin (μmol/L) 25.8 (13.4, 53.9) 35.4 (17.2, 69.7) 0.27
Base excess (mmol/L) −5.8 (−10.2, −4.1) −6.95 (−10.5, −4.6) 0.27
Blood HCO3 (mmol/L) 18.9 (17.1, 21.2) 18.6 (14.9, 20.4) 0.22
INR 1.7 (1.3, 2.1) 1.75 (1.5, 2.3) 0.3
Fibrinogen (g/L) 2.93 (2.37, 4.52) 3.16 (2.48, 4.27) 0.8
ALT (units/L) 38.4 (19, 103.4) 41.75 (23.5, 171) 0.32
AST (units/L) 118.7 (48.9, 247) 119.05 (54.7, 289.7) 0.55
Initial blood lactate (mmol/L) 8.9 (5.5, 11.2) 5.7 (4.6, 11.9) 0.02

After ECMO support
Peak blood lactate (mmol/L) 16.35 (10.9, 20) 17.8 (10.9, 25) 0.04
Blood lactate at T12 (mmol/L) 8.7 (4.7, 14.5) 5.8 (4.6, 15) 0.024
Blood lactate at T24 (mmol/L) 4.1 (2.3, 7) 2.9 (2.4, 11.4) 0.06
Lactate clearance % (LC-T12) 6.35 (−51.5, 40.6) 14.65 (−43.55, 38.3) < 0.001
Lactate clearance % (LC-T24) 52.08 (5.88, 64.43) 32.59 (−17.76, 65.52) 0.003
Platelet count 48 h (109/L) 81 (59, 124) 88 (72, 138.5) 0.39
Fibrinogen 48 h (g/L) 2.42 (1.91, 3.62) 2.56 (2.24, 3.83) 0.18
The 3rd day SOFA 14 (11, 16) 14 (9, 17) 0.9
The 5th day SOFA 15 (10, 18) 14 (8, 18) 0.74

Abbreviations: ALT: alanine transaminase, AST: aspartate aminotransferase, INR: international normalized ratio; SOFA, sequential organ failure assessment.