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. 2002 Aug 15;21(16):4277–4286. doi: 10.1093/emboj/cdf434

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Copyright © 2002 European Molecular Biology Organization

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graphic file with name cdf434f4.jpg — Fig. 4. Ectopic expression of Keren in wings and the ventral epidermis. (A) Wild-type wing. (B and C) Full-length UAS-Keren expressed in wings with the MS1096-Gal4 driver produced a range of EGF receptor hyperactivity phenotypes: thickened wing veins and extra wing vein material. (D–F) Expression of secreted Spitz in the embryo with the arm-Gal4 driver produced typical EGF receptor overactivation phenotypes in the ventral epidermis (Szüts et al., 1997; Payre et al., 1999). Wild-type denticle belts have a characteristic arrangement of six rows (D); overexpression of sSpi (E) or sKer (F) caused the formation of extra denticles.